(2-Phenoxypropan-2-yl)benzene

Base Information

• Chemical Name: (2-Phenoxypropan-2-yl)benzene
• CAS No.: 24318-48-7
• Molecular Formula: C15H16O
• Molecular Weight: 212.291
• DSSTox Substance ID: DTXSID40705805
• Nikkaji Number: J1.370.404J
• Wikidata: Q82638843
• Mol file: 24318-48-7.mol

Synonyms:(2-Phenoxypropan-2-yl)benzene;phenylcumyl ether;24318-48-7;Phenyl alpha-cumyl ether;SCHEMBL9331411;DTXSID40705805

Chemical Property of (2-Phenoxypropan-2-yl)benzene

Chemical Property:

• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 212.120115130
• Heavy Atom Count: 16
• Complexity: 198

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C1=CC=CC=C1)OC2=CC=CC=C2

Technology Process of (2-Phenoxypropan-2-yl)benzene

There total 4 articles about (2-Phenoxypropan-2-yl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

tetraphenylbismuth(V) fluoride + 1-methyl-1-phenylethyl alcohol (617-94-7) → 1-methyl-1-phenylethyl phenyl ether (24318-48-7)

Guidance literature:

With N-Methyldicyclohexylamine; copper diacetate; In toluene; at 20 ℃; for 1h;

DOI:10.1246/cl.2006.1140

Reference yield: 80.0%

Isopropylbenzene (98-82-8) + Phenyl acetate (122-79-2,34474-31-2) → 1-methyl-1-phenylethyl phenyl ether (24318-48-7)

Guidance literature:

With di-tert-butyl peroxide; C₂₈H₃₃CuN₂O₄; In neat (no solvent); at 90 ℃; for 24h; regioselective reaction; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1021/jacs.6b09057

Reference yield:

1-methyl-1-phenylethyl alcohol (617-94-7) + phenol (108-95-2,27073-41-2) → 1-methyl-1-phenylethyl phenyl ether (24318-48-7)

Guidance literature:

With acetophenone;

upstream raw materials:

1-methyl-1-phenylethyl alcohol

phenol

Isopropylbenzene

Phenyl acetate