5-Hydroxy-2-naphthoic acid

Base Information

Chemical Name:5-Hydroxy-2-naphthoic acid
CAS No.:2437-18-5
Molecular Formula:C11H8O3
Molecular Weight:188.183
Hs Code.:
DSSTox Substance ID:DTXSID20470483
Nikkaji Number:J94.846B
Wikidata:Q82298585
Mol file:2437-18-5.mol

Synonyms:5-hydroxy-2-naphthoic acid;2437-18-5;5-hydroxynaphthalene-2-carboxylic Acid;2-Naphthalenecarboxylic acid, 5-hydroxy-;SCHEMBL186327;DTXSID20470483;SMAMQSIENGBTRV-UHFFFAOYSA-N;MFCD18417858;1-hydroxynaphthalene-6-carboxylic acid;5-hydroxy-2-napthalene carboxylic acid;SY282882;FT-0719322

Suppliers and Price of 5-Hydroxy-2-naphthoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 5-Hydroxy-2-naphthoic acid

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:188.047344113
Heavy Atom Count:14
Complexity:227

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=C2)C(=O)O)C(=C1)O

Technology Process of 5-Hydroxy-2-naphthoic acid

There total 1 articles about 5-Hydroxy-2-naphthoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7,12-dioxo-7,12-dihydro-benz[a]anthracene-4-sulfonic acid ; potassium-salt

: 2437-18-5
5-hydroxy-2-naphthoic acid

: 65-85-0,8013-63-6
benzoic acid

Guidance literature:: at 260 ℃;

Reference yield:

: 2437-18-5
5-hydroxy-2-naphthoic acid

: 90-15-3
α-naphthol

: 124-38-9,18923-20-1
carbon dioxide

Guidance literature:

Reference yield:

: 2437-18-5
5-hydroxy-2-naphthoic acid

: C₂₉H₂₄N₂O₃

: C₂₉H₂₆N₂O₄

Guidance literature:: Multi-step reaction with 5 steps

1.1: 0.17 h / -20 °C

1.2: 19 h / -20 °C / Reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

3.1: N,N-dimethyl-formamide / 4.5 h / Reflux; Inert atmosphere

4.1: pyridinium chlorochromate / dichloromethane / 24 h / 20 °C / Inert atmosphere

5.1: Mg-Zr-Cs doped silica / dimethyl sulfoxide / 8 h

With lithium aluminium tetrahydride; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; 5.1: |Aldol Condensation;
DOI:10.1039/d0cy00806k