N-[4-[2-(4-acetamidophenyl)sulfonylethylsulfonyl]phenyl]acetamide

Base Information

• Chemical Name: N-[4-[2-(4-acetamidophenyl)sulfonylethylsulfonyl]phenyl]acetamide
• CAS No.: 52183-58-1
• Molecular Formula: C18H20 N2 O6 S2
• Molecular Weight: 424.499
• NSC Number: 85667
• DSSTox Substance ID: DTXSID10966547
• Wikidata: Q82948957
• Mol file: 52183-58-1.mol

Synonyms:52183-58-1;NSC85667;DTXSID10966547;NSC-85667;N,N'-[Ethane-1,2-diylbis(sulfonyl-4,1-phenylene)]diethanimidic acid

Chemical Property of N-[4-[2-(4-acetamidophenyl)sulfonylethylsulfonyl]phenyl]acetamide

Chemical Property:

• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 424.07627871
• Heavy Atom Count: 28
• Complexity: 685

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC=C(C=C1)S(=O)(=O)CCS(=O)(=O)C2=CC=C(C=C2)NC(=O)C

Technology Process of N-[4-[2-(4-acetamidophenyl)sulfonylethylsulfonyl]phenyl]acetamide

There total 8 articles about N-[4-[2-(4-acetamidophenyl)sulfonylethylsulfonyl]phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1,2-Di(4-acetamidophenylthio)ethane (93065-81-7) → 1,2-Di(4-acetamidophenylsulphono)ethane (52183-58-1)

Guidance literature:

With potassium permanganate; acetic acid; Ambient temperature;

Reference yield:

meso-2,3-dibromosuccinic acid (608-36-6) + water (7732-18-5) → 1,2-Di(4-acetamidophenylsulphono)ethane (52183-58-1)

Guidance literature:

Das Dinatriumsalz liefert;

DOI:10.1039/jr9450000826

Reference yield:

ethylene dibromide (106-93-4) → 1,2-Di(4-acetamidophenylsulphono)ethane (52183-58-1)

Guidance literature:

With ethanol;

DOI:10.1021/ja01223a003

upstream raw materials:

4-acetamidobenzenesulfinic acid

ethylene dibromide

sodium 4-acetamidobenzenesulfinate

diethylamine

Downstream raw materials:

1,2-disulfanilyl-ethane

1,2-Di(4-isothiocyanatophenylsulphono)ethane

Refernces