Acetamide, N-(4-bromophenyl)-2,2,2-trifluoro-

Base Information

• Chemical Name: Acetamide, N-(4-bromophenyl)-2,2,2-trifluoro-
• CAS No.: 24568-11-4
• Molecular Formula: C8H5BrF3NO
• Molecular Weight: 268.033
• Mol file: 24568-11-4.mol

Synonyms:p-bromotrifluoroacetanilide;N-p-Bromphenyltrifluoracetamid;Trifluoraceto-p-bromanilid;5-amino-2-bromobenzotrifluoride;N-(4-bromo-phenyl)-2,2,2-trifluoro-acetamide;Acetamide,N-(4-bromophenyl)-2,2,2-trifluoro;

Chemical Property of Acetamide, N-(4-bromophenyl)-2,2,2-trifluoro-

Chemical Property:

• PSA: 29.10000
• LogP: 3.02290

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetamide, N-(4-bromophenyl)-2,2,2-trifluoro-

There total 8 articles about Acetamide, N-(4-bromophenyl)-2,2,2-trifluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,2,2-trifluoroacetamide (354-38-1) + 1,4-bromoiodobenzene (589-87-7) → N-(4-bromophenyl)-2,2,2-trifluoro-acetamide (24568-11-4)

Guidance literature:

With potassium phosphate; N,N`-dimethylethylenediamine; copper(l) iodide; In N,N-dimethyl-formamide; at 45 ℃;

DOI:10.1016/j.tetlet.2007.11.012

Reference yield: 95.0%

4-bromo-aniline (106-40-1) + trifluoroacetic acid (76-05-1) → N-(4-bromophenyl)-2,2,2-trifluoro-acetamide (24568-11-4)

Guidance literature:

With bis(trichloromethyl) carbonate; triethylamine; In dichloromethane; at 20 ℃; for 0.25h;

DOI:10.2174/157017811797249317

Reference yield: 93.0%

4-bromo-aniline (106-40-1) + trifluoroacetic anhydride (407-25-0) → N-(4-bromophenyl)-2,2,2-trifluoro-acetamide (24568-11-4)

Guidance literature:

With pyridine; In dichloromethane;

DOI:10.1021/jo00099a049

upstream raw materials:

4-bromo-aniline

trifluoroacetic anhydride

trifluoroacetic acid

2,2,2-trifluoroacetamide

Downstream raw materials:

2,2,2-trifluoro-4'-phenylacetanilide

4-bromo-aniline

N-(4-bromo-phenyl)-N-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2,2,2-trifluoro-acetamide

4-(2,2,2-trifluroacetamide)phenylboronic acid