2-Amino-5-tert-butylbenzoic acid

Base Information

Chemical Name:2-Amino-5-tert-butylbenzoic acid
CAS No.:2475-77-6
Molecular Formula:C11H15NO2
Molecular Weight:193.246
Hs Code.:2922499990
European Community (EC) Number:837-286-9
DSSTox Substance ID:DTXSID00529549
Wikidata:Q82400034
Mol file:2475-77-6.mol

Synonyms:2-amino-5-tert-butylbenzoic acid;2475-77-6;2-Amino-5-tert-butyl-benzoic acid;Benzoic acid, 2-amino-5-(1,1-dimethylethyl)-;MFCD05664858;SCHEMBL1827375;2-amino-5-tert-butylbenzoicacid;DTXSID00529549;CAA47577;AKOS008118999;CS-0250910;EN300-52722;2-Amino-5-tert-butyl-benzoic acid, AldrichCPR;G54934;Z362758686

Suppliers and Price of 2-Amino-5-tert-butylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-amino-5-tert-butylbenzoicAcid
10mg
$ 45.00

American Custom Chemicals Corporation
2-AMINO-5-TERT-BUTYL-BENZOIC ACID 95.00%
5G
$ 1928.08

American Custom Chemicals Corporation
2-AMINO-5-TERT-BUTYL-BENZOIC ACID 95.00%
2.5G
$ 1473.14

American Custom Chemicals Corporation
2-AMINO-5-TERT-BUTYL-BENZOIC ACID 95.00%
1G
$ 983.52

AK Scientific
2-Amino-5-tert-butylbenzoicacid
250mg
$ 442.00

Total 8 raw suppliers

Chemical Property of 2-Amino-5-tert-butylbenzoic acid

Chemical Property:

Vapor Pressure:5.7E-05mmHg at 25°C
Melting Point:153-154 °C
Boiling Point:332.7oC at 760 mmHg
PKA:2.30±0.10(Predicted)
Flash Point:155oC
PSA：63.32000
Density:1.13g/cm3
LogP:2.84570
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:193.110278721
Heavy Atom Count:14
Complexity:220

Purity/Quality:

99% ^*data from raw suppliers

2-amino-5-tert-butylbenzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=C(C=C1)N)C(=O)O

Technology Process of 2-Amino-5-tert-butylbenzoic acid

There total 6 articles about 2-Amino-5-tert-butylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 2475-68-5
5-tert-butyl-2,3-dihydro-1H-indole-2,3-dione

: 2475-77-6
2-amino-5-(1,1-dimethylethyl)benzoic acid

Guidance literature:: With potassium chloride; dihydrogen peroxide; sodium hydroxide; In water; at -10 ℃; for 0.166667h; Inert atmosphere;
DOI:10.1016/j.jfluchem.2015.07.030

Reference yield:

: 60772-71-6
5-t-butyl-2-nitrobenzoic acid

: 2475-77-6
2-amino-5-(1,1-dimethylethyl)benzoic acid

Guidance literature:: palladium; In methanol;

Reference yield:

: 769-92-6
4-tert-Butylaniline

: 2475-77-6
2-amino-5-(1,1-dimethylethyl)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride; sodium sulfate; hydrogenchloride / water / 0.17 h / 55 °C / Inert atmosphere

2: sulfuric acid / 0.17 h / 80 °C / Inert atmosphere

3: sodium hydroxide; potassium chloride; dihydrogen peroxide / water / 0.17 h / -10 °C / Inert atmosphere

With hydrogenchloride; sulfuric acid; potassium chloride; hydroxylamine hydrochloride; dihydrogen peroxide; sodium sulfate; sodium hydroxide; In water;
DOI:10.1016/j.jfluchem.2015.07.030