3-Acetoxybenzoic acid methyl ester

Base Information

• Chemical Name: 3-Acetoxybenzoic acid methyl ester
• CAS No.: 24781-23-5
• Molecular Formula: C10H10O4
• Molecular Weight: 194.187
• Hs Code.: 2918990090
• Mol file: 24781-23-5.mol

Synonyms:m-methyl acetoxybenzoate;Methyl 3-(acetyloxy)benzoate;methyl 3-acetoxybenzoate;3-Acetoxy-benzoesaeure-methylester;3-Acetoxybenzoic acid methyl ester;Benzoic acid,3-(acetyloxy)-,methyl ester;

Chemical Property of 3-Acetoxybenzoic acid methyl ester

Chemical Property:

• Boiling Point: 291.1±23.0 °C(Predicted)
• PSA: 52.60000
• Density: 1.177±0.06 g/cm3(Predicted)
• LogP: 1.39850

Purity/Quality:

99% ^*data from raw suppliers

Methyl3-(acetyloxy)benzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Acetoxybenzoic acid methyl ester

There total 6 articles about 3-Acetoxybenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanol (67-56-1) + acetic anhydride (108-24-7) + 3-Carboxyphenol (99-06-9) → 3-acetoxybenzoic acid methyl ester (24781-23-5)

Guidance literature:

With sulfuric acid; for 4h; Reflux;

Reference yield: 96.0%

3-acetoxybenzoic acid (6304-89-8) + dimethyl dicarbonate (4525-33-1) → 3-acetoxybenzoic acid methyl ester (24781-23-5)

Guidance literature:

magnesium(II) perchlorate; In nitromethane; at 20 ℃; for 16h;

DOI:10.1002/adsc.200303040

Reference yield: 51.0%

methyl 3-iodo-benzoate (618-91-7) + nickel(II) acetate tetrahydrate (6018-89-9) + N-tert-butoxycarbonyl-proline (15761-39-4,59433-50-0) → benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) + 3-acetoxybenzoic acid methyl ester (24781-23-5) + 1-(tert-butyl) 2-(3-(methoxycarbonyl)phenyl)pyrrolidine-1,2-dicarboxylate

Guidance literature:

With N-isopropyl-N-tert-butylamine; 4,4'-di-tert-butyl-2,2'-bipyridine; In dimethyl sulfoxide; at 40 ℃; for 72h; Irradiation; Sealed tube;

DOI:10.1002/anie.201902785

upstream raw materials:

diazomethane

3-acetoxybenzoic acid

dimethyl dicarbonate

3-hydroxybenzoyl chloride

Downstream raw materials:

3-acetoxybenzoic acid