Ethyl 4-(4-oxopiperidin-1-yl)benzoate

Base Information

Chemical Name:Ethyl 4-(4-oxopiperidin-1-yl)benzoate
CAS No.:25437-95-0
Molecular Formula:C14H17NO3
Molecular Weight:247.294
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90507896
Wikidata:Q82364452
Mol file:25437-95-0.mol

Synonyms:Ethyl 4-(4-oxopiperidin-1-yl)benzoate;25437-95-0;ethyl 4-(4-oxo-1-piperidinyl)benzoate;Ethyl4-(4-oxopiperidin-1-yl)benzoate;SCHEMBL532250;Benzoic acid, 4-(4-oxo-1-piperidinyl)-, ethyl ester;DTXSID90507896;UWOUGBBALATQAZ-UHFFFAOYSA-N;AKOS015905058;ethyl 4-(4-oxo-1-piperidyl)benzoate;1-(4-ethoxycarbonylphenyl)-4-piperidone;4-(4-oxo-piperidin-1-yl)-benzoic acid ethyl ester;A1-21422

Suppliers and Price of Ethyl 4-(4-oxopiperidin-1-yl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl4-(4-oxopiperidin-1-yl)benzoate 95+%
1g
$ 589.00

Chemenu
ethyl4-(4-oxopiperidin-1-yl)benzoate 95%
1g
$ 557.00

A1 Biochem Labs
Ethyl4-(4-oxopiperidin-1-yl)benzoate 95%
2.5 g
$ 1150.00

Total 9 raw suppliers

Chemical Property of Ethyl 4-(4-oxopiperidin-1-yl)benzoate

Chemical Property:

PSA：46.61000
LogP:2.09760
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:247.12084340
Heavy Atom Count:18
Complexity:298

Purity/Quality:

99% ^*data from raw suppliers

Ethyl4-(4-oxopiperidin-1-yl)benzoate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=C(C=C1)N2CCC(=O)CC2

Technology Process of Ethyl 4-(4-oxopiperidin-1-yl)benzoate

There total 6 articles about Ethyl 4-(4-oxopiperidin-1-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 79421-38-8
4-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-benzoic acid ethyl ester

: 25437-95-0
4-(4-Oxo-1-piperidinyl)benzoic acid ethyl ester

Guidance literature:: With sulfuric acid; In tetrahydrofuran; for 96h; Ambient temperature;
DOI:10.1055/s-1981-29539

Reference yield: 66.0%

: 25437-94-9
ethyl 4-(4-hydroxypiperidin-1-yl)benzoate

: 25437-95-0
4-(4-Oxo-1-piperidinyl)benzoic acid ethyl ester

Guidance literature:: With pyridine; dimethyl sulfoxide; dicyclohexyl-carbodiimide; trifluoroacetic acid; In benzene; at 5 - 23 ℃; Cooling;

Reference yield:

: 451-46-7
4-fluorobenzoic acid ethyl ester

: 25437-95-0
4-(4-Oxo-1-piperidinyl)benzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / K₂CO₃ / acetonitrile / 96 h / Heating

2: 63 percent / N,N-Dicyclohexylcarbodiimide,DMSO, pyridine, trifluoroacetic acid / benzene / ice-water bath temp. - room temp., overnight

With pyridine; potassium carbonate; dimethyl sulfoxide; dicyclohexyl-carbodiimide; trifluoroacetic acid; In acetonitrile; benzene;
DOI:10.1055/s-1981-29539