Urea, N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]- N'-[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,6-bis(1-methylethyl) phenyl]-

Base Information

Chemical Name:Urea, N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]- N'-[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,6-bis(1-methylethyl) phenyl]-
CAS No.:259225-20-2
Molecular Formula:C39H54N4O4Si
Molecular Weight:670.968
Hs Code.:
Mol file:259225-20-2.mol

Urea,
N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]-
N'-[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,6-bis(1-methylethyl)
phenyl]-

Synonyms:

Suppliers and Price of Urea, N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]- N'-[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,6-bis(1-methylethyl) phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Urea, N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]- N'-[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,6-bis(1-methylethyl) phenyl]-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Urea, N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]- N'-[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,6-bis(1-methylethyl) phenyl]-

There total 9 articles about Urea, N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]- N'-[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,6-bis(1-methylethyl) phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 259225-36-0
4-(tert-butyl-dimethyl-silanyloxymethyl)-2,6-diisopropyl-phenylamine

: 873194-72-0
[1-butyl-4-(3-methoxy-phenyl)-2-oxo-1,2-dihydro-[1,8]naphthyridin-3-yl]-carbamic acid phenyl ester

: 259225-20-2
N-[1-butyl-4-(3-methoxyphenyl)-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N'-[2,6-diisopropyl-4-(tert-butyldimethylsilyloxymethyl)phenyl]urea

Guidance literature:: With dmap; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmcl.2005.09.056

Reference yield:

: 24544-04-5
2,6-diisopropylbenzenamine

: 259225-20-2
N-[1-butyl-4-(3-methoxyphenyl)-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N'-[2,6-diisopropyl-4-(tert-butyldimethylsilyloxymethyl)phenyl]urea

Guidance literature:: Multi-step reaction with 5 steps

1: 91 percent / aq. HIO₃; I₂; acetic acid / H₂SO₄ / 5 h / 80 °C

2: 83 percent / Pd(OAc)2; DPP; Et₃N / dimethylformamide / 4 h / 80 °C

3: 98 percent / LiAlH₄ / tetrahydrofuran / 0.5 h / 60 °C

4: 83 percent / DMAP; Et₃N / CH₂Cl₂ / 20 °C

5: 73 percent / DMAP / dimethylformamide / 20 °C

With dmap; palladium diacetate; lithium aluminium tetrahydride; parathion; iodine; iodic acid; acetic acid; triethylamine; sulfuric acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.09.056

Reference yield:

: 664340-51-6
4-amino-3,5-diisopropylbenzenemethanol

: 259225-20-2
N-[1-butyl-4-(3-methoxyphenyl)-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N'-[2,6-diisopropyl-4-(tert-butyldimethylsilyloxymethyl)phenyl]urea

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / DMAP; Et₃N / CH₂Cl₂ / 20 °C

2: 73 percent / DMAP / dimethylformamide / 20 °C

With dmap; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.09.056