3-(4-Trifluoromethoxy-phenyl)-acrylamide

Base Information

Chemical Name:3-(4-Trifluoromethoxy-phenyl)-acrylamide
CAS No.:259269-56-2
Molecular Formula:C10H8F3NO2
Molecular Weight:231.174
Hs Code.:
DSSTox Substance ID:DTXSID70381833
Mol file:259269-56-2.mol

Synonyms:3-(4-Trifluoromethoxy-phenyl)-acrylamide;DTXSID70381833

Suppliers and Price of 3-(4-Trifluoromethoxy-phenyl)-acrylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Methyl 2'-fluoro-1,1'-biphenyl-4-carboxylate
1 g
$ 256.00

SynQuest Laboratories
Methyl 2'-fluoro-1,1'-biphenyl-4-carboxylate
5 g
$ 1024.00

American Custom Chemicals Corporation
3-[4-(TRIFLUOROMETHOXY)PHENYL]ACRYLAMIDE 95.00%
5MG
$ 498.97

Total 3 raw suppliers

Chemical Property of 3-(4-Trifluoromethoxy-phenyl)-acrylamide

Chemical Property:

Boiling Point:353.0±42.0 °C(Predicted)
PKA:15.42±0.50(Predicted)
PSA：53.31000
Density:1.347±0.06 g/cm3(Predicted)
LogP:3.23340
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:231.05071298
Heavy Atom Count:16
Complexity:268

Purity/Quality:

99% ^*data from raw suppliers

Methyl 2'-fluoro-1,1'-biphenyl-4-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C=CC(=O)N)OC(F)(F)F

Technology Process of 3-(4-Trifluoromethoxy-phenyl)-acrylamide

There total 1 articles about 3-(4-Trifluoromethoxy-phenyl)-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 783-13-1
4-trifluoromethoxycinnamic acid

: 259269-56-2
3-(4-trifluoromethoxy-phenyl)-acrylamide

Guidance literature:: p-trifluoromethoxycinnamic acid; With oxalyl dichloride; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 2.66667h;

With ammonia; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); water; at 0 - 5 ℃; for 0.75h;