N-(3-Chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-2-hydroxybenzamide

Base Information

Chemical Name:N-(3-Chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-2-hydroxybenzamide
CAS No.:87444-09-5
Molecular Formula:C₁₇H₁₅ClN₂O₄
Molecular Weight:346.77
Hs Code.:
DSSTox Substance ID:DTXSID601007568
Mol file:87444-09-5.mol

Synonyms:87444-09-5;BRN 5999847;N-(3-Chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-2-hydroxybenzamide;Benzamide, N-(3-chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-2-hydroxy-;N-[3-chloro-2-(2-methoxyphenyl)-4-oxoazetidin-1-yl]-2-hydroxybenzamide;N-(3-Chloro-2-(2-methoxyphenyl)-4-oxoazetidin-1-yl)-2-hydroxybenzamide;DTXSID601007568;N-[3-CHLORO-2-(2-METHOXYPHENYL)-4-OXO-AZETIDIN-1-YL]-2-HYDROXY-BENZAMI DE;LS-26129;N-[3-Chloro-2-(2-methoxyphenyl)-4-oxoazetidin-1-yl]-2-hydroxybenzene-1-carboximidic acid

Suppliers and Price of N-(3-Chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-2-hydroxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(3-Chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-2-hydroxybenzamide

Chemical Property:

PSA：82.36000
Density:1.46g/cm³
LogP:2.74920
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:346.0720347
Heavy Atom Count:24
Complexity:489

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1C2C(C(=O)N2NC(=O)C3=CC=CC=C3O)Cl

Technology Process of N-(3-Chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-2-hydroxybenzamide

There total 3 articles about N-(3-Chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-2-hydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 18176-35-7
salicylic acid-(2-methoxy-benzylidenehydrazide)

: 79-04-9
chloroacetyl chloride

: 87444-09-5
N-[3-Chloro-2-(2-methoxy-phenyl)-4-oxo-azetidin-1-yl]-2-hydroxy-benzamide

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; for 3h; Heating;
DOI:10.1002/ardp.19843170707

Reference yield:

: 936-02-7
2-Hydroxybenzoylhydrazine

: 87444-09-5
N-[3-Chloro-2-(2-methoxy-phenyl)-4-oxo-azetidin-1-yl]-2-hydroxy-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: glacial CH₃COOH / 2 h / Heating

2: 52 percent / triethylamine / dimethylformamide / 3 h / Heating

With acetic acid; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1002/ardp.19843170707

Reference yield:

: 135-02-4
ortho-anisaldehyde

: 87444-09-5
N-[3-Chloro-2-(2-methoxy-phenyl)-4-oxo-azetidin-1-yl]-2-hydroxy-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: glacial CH₃COOH / 2 h / Heating

2: 52 percent / triethylamine / dimethylformamide / 3 h / Heating

With acetic acid; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1002/ardp.19843170707