Boronic acid, [2-[[(3-methylphenyl)amino]methyl]phenyl]-

Base Information

• Chemical Name: Boronic acid, [2-[[(3-methylphenyl)amino]methyl]phenyl]-
• CAS No.: 262352-25-0
• Molecular Formula: C14H16BNO2
• Molecular Weight: 241.098
• Mol file: 262352-25-0.mol

Synonyms:(2-boronobenzyl)-m-tolylamine;

Chemical Property of Boronic acid, [2-[[(3-methylphenyl)amino]methyl]phenyl]-

Chemical Property:

• Melting Point: 72 - 73 °C
• PSA: 52.49000
• LogP: 1.35990

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boronic acid, [2-[[(3-methylphenyl)amino]methyl]phenyl]-

There total 8 articles about Boronic acid, [2-[[(3-methylphenyl)amino]methyl]phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

N-(2-dihydroxyborylbenzyl)-[3-methyl-4-(4-nitrophenylazo)phenyl]amine → N-(2-dihydroxyborylbenzyl)-m-tolylamine (262352-25-0)

Guidance literature:

N-(2-dihydroxyborylbenzyl)-[3-methyl-4-(4-nitrophenylazo)phenyl]amine; With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;

With hydrogenchloride; In methanol; water; for 0.5h; Further stages.;

DOI:10.1021/ol016923w

Reference yield: 81.0%

N-(2-dihydroxyborylbenzylidene)-m-tolylamine → N-(2-dihydroxyborylbenzyl)-m-tolylamine (262352-25-0)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;

DOI:10.1039/b108896c

Reference yield: 81.0%

sodium tetrahydroborate (16940-66-2) + N-(2-dihydroxyborylbenzylidene)-m-tolylamine (327096-47-9) → N-(2-dihydroxyborylbenzyl)-m-tolylamine (262352-25-0)

Guidance literature:

In methanol; NaBH4 was added slowly to Schiff base in dry methanol and stirred at room temp. for 2 h; react. mixt. was poured into ice-water, HCl was added slowly and stirredfor 30 min, ppt. was filtered; elem. anal.;

DOI:10.1039/b108896c

upstream raw materials:

N-(2-dihydroxyborylbenzylidene)-m-tolylamine

2-formylbenzene boronic acid

1-amino-3-methylbenzene

sodium tetrahydroborate

Downstream raw materials:

4-[4-(2-dihydroxyborylbenzylamino)-2-methylphenylazo]benzenesulfonic acid

3-[4-(2-dihydroxyborylbenzylamino)-2-methylphenylazo]benzoic acid

N-(2-dihydroxyborylbenzyl)-[4-(4-methoxyphenylazo)-3-methylphenyl]amine

4-[4-(2-dihydroxyborylbenzylamino)-2-methylphenylazo]benzoic acid