BENZYLTERT-BUTYLSULFOXIDE

Base Information

• Chemical Name: BENZYLTERT-BUTYLSULFOXIDE
• CAS No.: 26756-22-9
• Molecular Formula: C11H16OS
• Molecular Weight: 196.313
• Hs Code.: 2930909090
• Mol file: 26756-22-9.mol

Synonyms:(+/-)-benzyl tert-butyl sulfoxide;[(t-butylsulfinyl)methyl]benzene;tert-butyl phenylmethyl sulfoxide;rac-benzyl tert-butyl sulfoxide;Benzene,[[(1,1-dimethylethyl)sulfinyl]methyl];[(tert-butylsulfinyl)methyl]benzene;(S) benzyl t-butyl sulphoxide;

Chemical Property of BENZYLTERT-BUTYLSULFOXIDE

Chemical Property:

• Melting Point: 74-75 °C
• Boiling Point: 347.6±21.0 °C(Predicted)
• PSA: 36.28000
• Density: 1.082±0.06 g/cm3(Predicted)
• LogP: 3.59950

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BENZYLTERT-BUTYLSULFOXIDE

There total 15 articles about BENZYLTERT-BUTYLSULFOXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl t-butyl sulfide (7417-73-4) → Benzyl tert-butyl sulfoxide (26756-22-9)

Guidance literature:

With propan-1-ol; dihydrogen peroxide; In methanol; for 24h;

DOI:10.1055/s-1990-27059

Reference yield: 89.0%

phenylmethanethiol (100-53-8) + tert-butyl alcohol (75-65-0) → Benzyl tert-butyl sulfoxide (26756-22-9)

Guidance literature:

phenylmethanethiol; tert-butyl alcohol; With perchloric acid; acetic anhydride; acetic acid; at 20 ℃; for 24h; Cooling with ice;

With dihydrogen peroxide; at 0 - 20 ℃; for 8h;

DOI:10.1002/adsc.201500368

Reference yield: 79.0%

3-(tert-butylsulfinyl)propionic acid ethyl ester (49833-28-5) + benzyl bromide (100-39-0) → Benzyl tert-butyl sulfoxide (26756-22-9)

Guidance literature:

3-(tert-butylsulfinyl)propionic acid ethyl ester; With potassium tert-butylate; In tetrahydrofuran; at -78 ℃; for 0.333333h;

benzyl bromide; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1021/jo0478003

upstream raw materials:

benzyl t-butyl sulfide

ethyl ((R_S)-N-tert-butylsulfinyl)iminoacetate

benzylmagnesium chloride

perchloric acid

Downstream raw materials:

(R^*_S,2R^*)-2-(tert-butylsulfinyl)-1,1,2-triphenylethanol

(3S,4R)-3-Methyl-4-(2-methyl-propane-2-sulfinyl)-4-phenyl-butyric acid methyl ester

α-deuteriobenzyl t-butyl sulfoxides

(3R,4R)-4-(2-Methyl-propane-2-sulfinyl)-3,4-diphenyl-butyric acid methyl ester