1-Benzyl-5,6-dihydro-1h-imidazo[4,5-d]pyridazine-4,7-dione

Base Information

Chemical Name:1-Benzyl-5,6-dihydro-1h-imidazo[4,5-d]pyridazine-4,7-dione
CAS No.:5424-28-2
Molecular Formula:C12H10 N4 O2
Molecular Weight:242.237
Hs Code.:
NSC Number:12133
DSSTox Substance ID:DTXSID00279299
Wikidata:Q82011790

Synonyms:5424-28-2;1-benzyl-5,6-dihydro-1h-imidazo[4,5-d]pyridazine-4,7-dione;NSC12133;Oprea1_352033;SCHEMBL23461937;DTXSID00279299;NSC 12133;NSC-12133

Suppliers and Price of 1-Benzyl-5,6-dihydro-1h-imidazo[4,5-d]pyridazine-4,7-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-Benzyl-5,6-dihydro-1h-imidazo[4,5-d]pyridazine-4,7-dione

Chemical Property:

Density:1.51g/cm³
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:242.08037557
Heavy Atom Count:18
Complexity:354

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C=NC3=C2C(=O)NNC3=O

Technology Process of 1-Benzyl-5,6-dihydro-1h-imidazo[4,5-d]pyridazine-4,7-dione

There total 4 articles about 1-Benzyl-5,6-dihydro-1h-imidazo[4,5-d]pyridazine-4,7-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 321970-25-6
1-benzyl-1H-imidazole-4,5-dicarboxylic acid dimethyl ester

: 5424-28-2
1-benzyl-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione

Guidance literature:: With hydrazine hydrate; In ethanol; at 100 ℃; for 16h; Reflux;

Reference yield:

: 100-39-0
benzyl bromide

: 5424-28-2
1-benzyl-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C

1.2: 1.5 h / 20 °C

2.1: hydrazine hydrate / ethanol / 16 h / 100 °C / Reflux

With sodium hydride; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 3304-70-9
dimethyl imidazole-4,5-dicarboxylate

: 5424-28-2
1-benzyl-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C

1.2: 1.5 h / 20 °C

2.1: hydrazine hydrate / ethanol / 16 h / 100 °C / Reflux

With sodium hydride; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;