2-(4-Nitrophenoxy)-Propanoic Acid Ethyl Ester

Base Information

Chemical Name:2-(4-Nitrophenoxy)-Propanoic Acid Ethyl Ester
CAS No.:28059-69-0
Molecular Formula:C11H13NO5
Molecular Weight:239.228
Hs Code.:
Mol file:28059-69-0.mol

Synonyms:2-(4-Nitrophenoxy)-Propanoic Acid Ethyl Ester;2-(4-Nitro-phenoxy)-propionsaeure-aethylester;Ethyl-2-(4-nitrophenoxy)propionat;α-(4-Nitro-phenoxy)-propionsaeure-aethylester;

Suppliers and Price of 2-(4-Nitrophenoxy)-Propanoic Acid Ethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Nitrophenoxy)-PropanoicAcidEthylEster
1g
$ 165.00

Medical Isotopes, Inc.
2-(4-Nitrophenoxy)-PropanoicAcidEthylEster
10 g
$ 2200.00

Total 1 raw suppliers

Chemical Property of 2-(4-Nitrophenoxy)-Propanoic Acid Ethyl Ester

Chemical Property:

Boiling Point:355.2±17.0 °C(Predicted)
PSA：81.35000
Density:1.225±0.06 g/cm3(Predicted)
LogP:2.44840

Purity/Quality:: 2-(4-Nitrophenoxy)-PropanoicAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-(4-Nitrophenoxy)-Propanoic Acid Ethyl Ester is used in the smiles’ rearrangement on borohydride reduction of nitrophenoxy esters.

Technology Process of 2-(4-Nitrophenoxy)-Propanoic Acid Ethyl Ester

There total 6 articles about 2-(4-Nitrophenoxy)-Propanoic Acid Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 535-11-5,41978-69-2
Ethyl 2-bromopropionate

: 28059-69-0
2-(4-nitro-phenoxy)-propionic acid ethyl ester

Guidance literature:: With potassium carbonate; In acetonitrile; for 1h; Reflux;
DOI:10.1002/ardp.202100399

Reference yield: 29.0%

: 6111-99-5
ethyl diazoalaninate

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 28059-69-0
2-(4-nitro-phenoxy)-propionic acid ethyl ester

Guidance literature:: With tetrakis(acetonitrile)copper(I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate; C₂₀H₃₆N₂O₇; potassium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; In chloroform; at 40 ℃; for 2.5h; Inert atmosphere; Schlenk technique; Molecular sieve;
DOI:10.1039/d0cc00224k

Reference yield:

: 609-14-3
2-acetylpropanoic acid ethyl ester

: 28059-69-0
2-(4-nitro-phenoxy)-propionic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene; 4-acetamidobenzenesulfonyl azide / acetonitrile / 9 h / 0 - 20 °C / Inert atmosphere

2: C₂₀H₃₆N₂O₇; tetrakis(acetonitrile)copper(I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate; potassium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate / chloroform / 2.5 h / 40 °C / Inert atmosphere; Schlenk technique; Molecular sieve

With tetrakis(acetonitrile)copper(I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate; 4-acetamidobenzenesulfonyl azide; C₂₀H₃₆N₂O₇; 1,8-diazabicyclo[5.4.0]undec-7-ene; potassium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; In chloroform; acetonitrile;
DOI:10.1039/d0cc00224k