Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

Name	Prothanon	EINECS	1308068-626-2
CAS No.	13754-56-8	Density	1.224 g/cm³
PSA	49.00000	LogP	4.06680
Solubility	N/A	Melting Point	127-129 °C
Formula	C₁₇H₂₀N₂O₂S	Boiling Point	478.451 °C at 760 mmHg
Molecular Weight	352.885	Flash Point	243.159 °C
Transport Information	N/A	Appearance	white powder
Safety		Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	Phenothiazine,10-[2-(dimethylamino)propyl]-, 5,5-dioxide (8CI);9,9-Dioxopromethazine;9,9-Dioxypromethazin;Promethazine 5,5-dioxide;10H-Phenothiazine-10-ethanamine,N,N,a-trimethyl-, 5,5-dioxide;	Article Data	10

Prothanon Chemical Properties

IUPAC Name: 1-(5,5-Dioxophenothiazin-10-yl)-N,N-dimethylpropan-2-amine
Canonical SMILES: CC(CN1C2=CC=CC=C2S(=O)(=O)C3=CC=CC=C31)N(C)C
InChI: InChI=1S/C17H20N2O2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)22(20,
21)17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
InChIKey: FDXKCOBAFGSMDJ-UHFFFAOYSA-N
Molecular Weight: 316.4179 [g/mol]
Molecular Formula: C₁₇H₂₀N₂O₂S
XLogP3: 3.5
H-Bond Donor: 0
H-Bond Acceptor: 4
Index of Refraction: 1.605
Molar Refractivity: 89.11 cm³
Molar Volume: 258.4 cm³
Surface Tension: 46.5 dyne/cm
Density: 1.224 g/cm³
Flash Point: 243.2 °C
Enthalpy of Vaporization: 74.26 kJ/mol
Boiling Point: 478.5 °C at 760 mmHg
Vapour Pressure of Dioxopromethazine hydrochloride (CAS NO.13754-56-8): 2.57E-09 mmHg at 25 °C

Prothanon Uses

Dioxopromethazine hydrochloride (CAS NO.13754-56-8) is used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.

Prothanon Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
guinea pig	LD50	intravenous	8mg/kg (8mg/kg)	Pharmazie. Vol. 25, Pg. 91, 1970.
guinea pig	LD50	oral	225mg/kg (225mg/kg)	Pharmazie. Vol. 25, Pg. 91, 1970.
guinea pig	LD50	subcutaneous	33mg/kg (33mg/kg)	Pharmazie. Vol. 25, Pg. 91, 1970.
mouse	LD50	intraperitoneal	49mg/kg (49mg/kg)	Pharmazie. Vol. 25, Pg. 91, 1970.
mouse	LD50	intravenous	16mg/kg (16mg/kg)	Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 18, Pg. 155, 1983.
mouse	LD50	oral	50mg/kg (50mg/kg)	Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 18, Pg. 155, 1983.
mouse	LD50	subcutaneous	96mg/kg (96mg/kg)	Pharmazie. Vol. 25, Pg. 91, 1970.
rabbit	LD50	oral	165mg/kg (165mg/kg)	Pharmazie. Vol. 25, Pg. 91, 1970.

Prothanon Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NO_x, SO_x, and HCl.

Prothanon Specification

Dioxopromethazine hydrochloride (CAS NO.13754-56-8), its Synonyms are 5,5-Dioxo-10-(2-(dimethylamino)propyl)phenothiazine hydrochloride ; 9,9-Dioxo-10-(2-dimethylaminopropyl)-phenothiazinhydrochlorid ; 9,9-Dioxopromethazine ; 9,9-Dioxypromethazin ; Dioxopromethazin ; Dioxoprothazin ; Promethazine 5,5-dioxide ; Promethazine SS oxide ; Prothanon ; 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5,5-dioxide (9CI) ; 10H-Phenothiazine-10-ethanamine,N,N,alpha-trimethyl-,5,5-dioxide ; Phenothiazine, 10-(2-(dimethylamino)propyl)-, 5,5-dioxide, monohydrochloride ; Phenothizine, 10-(2-(dimethylamino)propyl)-, 5,5-dioxide (8CI) ; Dioxopromethazine .

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 13754-56-8