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Cas Database |
| Name |
Protopine |
EINECS | 204-999-6 |
| CAS No. | 130-86-9 | Density | 1.324 g/cm3 |
| PSA | 57.23000 | LogP | 2.49520 |
| Solubility | Insoluble in water | Melting Point |
211oC |
| Formula | C20H19NO5 | Boiling Point | 547.479 °C at 760 mmHg |
| Molecular Weight | 353.375 | Flash Point | 284.905 °C |
| Transport Information | UN 1544 | Appearance | Off-white solid |
| Safety | 24/25 | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
7,13a-Secoberbin-13a-one,7-methyl-2,3:9,10-bis(methylenedioxy)- (8CI);Protopine (6CI);Biflorine;Corydinine;Fumarine;Macleyine;Protopin; |
Article Data | 8 |
Protopine Chemical Properties
Chemical Name: Protopine
CAS No.: 130-86-9
EINECS: 204-999-6
RTECS Class: Agricultural Chemical and Pesticide
Molecular Formula: C20H19NO5
Molecular Weight: 353.37 g/mol
Density: 1.323 g/cm3
Flash Point: 284.9 °C
Boiling Point: 547.5 °C at 760 mmHg
Following is the structure of Fumarine (130-86-9):
The chemical synonymous of Fumarine (130-86-9) are 7,13a-Secoberbin-13a-one, 7-Methyl-2,3:9,10-bis(methylenedioxy)- ; 7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-C:5,6-G]azecin-15(7h)-one ; Biflorine ; Bis[1,3]Benzodioxolo[4,5-C:5',6'-G]azecin-13(5H)-one, 4,6,7,14-Tetrahydro-5-methyl- ; Corydinine ; Hypercorine ; Protopin ; Biflorin
Protopine Toxicity Data With Reference
| 1. | ipr-rat LDLo:100 mg/kg | NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),24. | ||
| 2. | ipr-mus LD50:482 mg/kg | YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. 16 (6)(1981),7. | ||
| 3. | orl-gpg LD50:237 mg/kg | THERAP Therapie. 28 (1973),767. | ||
| 4. | ipr-gpg LD50:116 mg/kg | THERAP Therapie. 28 (1973),767. |
Protopine Safety Profile
Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
Attention:
1. Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
2. Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
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