Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

Name	Pyrimidine	EINECS	206-026-0
CAS No.	289-95-2	Density	1.055 g/cm³
PSA	25.78000	LogP	0.47660
Solubility	soluble in water	Melting Point	19-22 °C(lit.)
Formula	C₄H₄N₂	Boiling Point	122.4 °C at 760 mmHg
Molecular Weight	80.0892	Flash Point	31.1 °C
Transport Information	UN 1993 3/PG 3	Appearance	white solid or colourless liquid
Safety	23-24/25-16	Risk Codes	10
Molecular Structure		Hazard Symbols	R10:;
Synonyms	m-Diazine;Pyrimidine (in DNA);1,3-Diazine;Miazine;Metadiazine;1,3-Diazabenzene;10008-95-4;1, 3-Diazabenzene;MiaskiteMiazine;Pyrimide;	Article Data	105

Pyrimidine Synthetic route

: 1450-85-7
2-thioxopyrimidine

: 289-95-2
PYRIMIDINE

Conditions

Conditions	Yield
With dihydrogen peroxide; acetic acid at 25℃; for 0.0833333h;	85%
With ozone In acetic acid at 25℃; for 0.5h;	64%
With ozone In acetic acid at 25℃; for 0.5h;	64%

: 4595-59-9
5-bromopyrimidine

A: 289-95-2
PYRIMIDINE

B: 31458-33-0
5-methoxypyrimidine

Conditions

Conditions	Yield
With sodium methylate In methanol; ethyl acetate	A n/a B 70%

: 591-55-9
pyrimidin-5-amine

: 289-95-2
PYRIMIDINE

Conditions

Conditions	Yield
With isopentyl nitrite In tetrahydrofuran at 120℃; under 5250.53 Torr; for 0.333333h;	55%

: 4595-59-9
5-bromopyrimidine

: 289-95-2
PYRIMIDINE

Conditions

Conditions	Yield
With triethylamine In methanol; water at 4℃; for 24h; Irradiation; sensitizer: methylene blue;	52%
With methyl phenylphosphinate; tetrabutylammomium bromide; tetra-(n-butyl)ammonium iodide; ethylene dibromide; triethylamine In N,N-dimethyl-formamide; acetonitrile at 20℃; Electrochemical reaction;

: 81454-19-5
2,4-Diphenyl-1-pyrimidin-2-yl-5,6-dihydro-benzo[h]quinolinium; fluoride

A: 289-95-2
PYRIMIDINE

B: 34987-58-1
2,4-diphenylbenzo[h]quinoline

Conditions

Conditions	Yield
With 2,4,6-triphenylpyridine at 250℃; for 6h;	A 51% B n/a

: 17043-94-6
pyrimidine N-oxide

: 54439-99-5
tert-butyl-isopropyl-thioketene

A: 289-95-2
PYRIMIDINE

B: 63702-81-8
3-tert-butyl-3-isopropylthiirane-2-one

Conditions

Conditions	Yield
In chloroform-d1 for 168h; Ambient temperature; study of sulfur transfer reaction;	A 50% B 44%

: 1-mercaptopyrimidine

: 18997-19-8
Chloromethyl pivalate

A: 289-95-2
PYRIMIDINE

B: 80693-26-1
2-Pivalyloxymethylthiopyrimidine

Conditions

Conditions	Yield
With triethylamine In dichloromethane	A 49% B n/a

: 90210-54-1
2-Benzyl-pyrimidine 1-oxide

A: 289-95-2
PYRIMIDINE

B: 5053-43-0
2-methylpyrimidine

C: 90210-57-4
benzyl-pyrimidine

D: 245-46-5
pyrimido[1,2-a]indole

Conditions

Conditions	Yield
at 800℃; under 0.0001 - 0.0006 Torr;	A 2% B n/a C 17% D 48%

: 90210-55-2
4-Benzyl-pyrimidine 3-oxide

A: 289-95-2
PYRIMIDINE

B: 3438-46-8
4-Methylpyrimidine

C: 64660-82-8
4-benzylpyrimidine

D: 23989-28-8
pyrimido-[1,6-a]indole

Conditions

Conditions	Yield
at 800℃; under 0.0001 - 0.0006 Torr;	A 14% B n/a C 13% D 45%

: 3934-20-1
2,6-Dichloropyrimidine

: 289-95-2
PYRIMIDINE

Conditions

Conditions	Yield
With sodium hydroxide; palladium on activated charcoal; diethyl ether Hydrogenation;
With palladium on activated charcoal; ethanol; magnesium oxide Hydrogenation;

Pyrimidine Chemical Properties

Molecular structure of Pyrimidine (CAS NO.289-95-2) is:

Product Name: Pyrimidine
CAS Registry Number: 289-95-2
IUPAC Name: pyrimidine
Molecular Weight: 80.08796 [g/mol]
Molecular Formula: C₄H₄N₂
XLogP3: -0.4
H-Bond Donor: 0
H-Bond Acceptor: 2
EINECS: 206-026-0
Melting Point: 19-22 °C(lit.)
Surface Tension: 44.1 dyne/cm
Density: 1.055 g/cm³
Flash Point: 31.1 °C
Enthalpy of Vaporization: 43.09 kJ/mol
Boiling Point: 122.4 °C at 760 mmHg
Vapour Pressure: 16.8 mmHg at 25°C
Refractive index: n20/D 1.504(lit.)
Storage temp.: Flammables area
Water Solubility: soluble
Sensitive: Hygroscopic
Stability: Stable, but air-sensitive and hygroscopic. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents, carbon dioxide. Flammable.
Product Categories: Pyrimidine;APIs & Intermediate;Boronic ester;Organoborons;Organohalides;Halogenated;Building Blocks;Nucleic acids;Halides;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Heterocyclic Building Blocks;Pyrimidines

Pyrimidine Uses

Pyrimidine (CAS NO.289-95-2) is used for pharmaceutical intermediates, raw materials of photosensitive agent, etc

Pyrimidine Production

Pyrimidine (CAS NO.289-95-2) can also be prepared within the laboratory by organic synthesis. One method is the classic Biginelli reaction. Many other methods rely on condensation of carbonyls with amines for instance the synthesis of 2-Thio-6-methyluracil from thiourea and ethyl acetoacetate or the synthesis of 4-methylpyrimidine with 4,4-dimethoxy-2-butanone and formamide.

Pyrimidine Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	3310mg/kg (3310mg/kg)		Progress in Biochemical Pharmacology. Vol. 1, Pg. 542, 1965.

Pyrimidine Safety Profile

Risk Statements: 10
R10:Flammable.
Safety Statements: 23-24/25-16
S23:Do not breathe vapour.
S24/25:Avoid contact with skin and eyes.
S16:Keep away from sources of ignition.
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
RTECS: UV6263000
HazardClass: 3
PackingGroup: III

Pyrimidine Specification

Pyrimidine , its cas register number is 289-95-2. It also can be called 1,3-Diazabenzene ; 1,3-Diazine ; Metadiazine ; Miazine ; m-Diazine .It is a colourless to pale yellow liquid. It is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. It is isomeric with two other forms of diazine.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 289-95-2