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Cas Database |
| Name |
Pyronaridine |
EINECS | 1533716-785-6 |
| CAS No. | 74847-35-1 | Density | 1.37g/cm3 |
| PSA | 76.72000 | LogP | 5.44880 |
| Solubility |
Stability
Toxicology
Toxicity data |
Melting Point |
N/A |
| Formula | C29H32 Cl N5 O2 | Boiling Point | 657.2oC at 760 mmHg |
| Molecular Weight | 518.058 | Flash Point | 351.3oC |
| Transport Information | N/A | Appearance | solid |
| Safety | Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl− and NOx. An antimalarial drug. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Benzo[b]-1,5-naphthyridine,phenol deriv.; Malaridine; Pyronaridine |
Article Data | 6 |
Pyronaridine Chemical Properties
IUPAC Name: 4-[(7-Chloro-2-methoxy-1,5-dihydrobenzo[b][1,5]naphthyridin-10-yl)imino]-2,6-bis(pyrrolidin-1-ylmethyl)cyclohexa-2,5-dien-1-one
The MF of Pyronaridine (CAS NO.74847-35-1) is C29H32ClN5O2.
The MW of Pyronaridine (CAS NO.74847-35-1) is 518.0497.
Synonyms of Pyronaridine (CAS NO.74847-35-1): 4-[(7-Chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol ; Phenol, 4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyrrolidinylmethyl)-
Stability: Incompatible with strong oxidizing agents
Index of Refraction: 1.719
Apperance: solid
Density: 1.356 g/ml
Flash Point: 329.6 °C
Boiling Point: 621.3 °C
Pyronaridine Uses
Pyronaridine (CAS NO.74847-35-1) is an antimalarial drug. It was first synthesized in 1970 and has been in clinical use in China since the 1980s.
Pyronaridine Toxicity Data With Reference
| 1. | mmo-sat 100 µg/plate | CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 3 (1982),51. | ||
| 2. | orl-mus LD50:1100 mg/kg | YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. 17 (1982),401. |
Pyronaridine Safety Profile
Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl− and NOx. An antimalarial drug.
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