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| CAS No.: | 10453-86-8 |
|---|---|
| Name: | RESMETHRIN |
| Molecular Structure: | |
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| Formula: | C22H26 O3 |
| Molecular Weight: | 338.447 |
| Synonyms: | Cyclopropanecarboxylicacid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, [5-(phenylmethyl)-3-furanyl]methylester (9CI); Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-,(5-benzyl-3-furyl)methyl ester (8CI); 3-Furanmethanol, 5-benzyl-,2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate (8CI);(5-Benzyl-3-furyl)methyl2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate;(5-Benzyl-3-furyl)methyl chrysanthemate; (5-Benzyl-3-furyl)methyl-DL-cis,trans-chrysanthemate; 5-Benzyl-3-furylmethyl (?à)-cis-trans-chrysanthemate; 5-Benzylfurfuryl chrysanthemate;ARI-B; Chrysron; Crossfire; Enforcer; NIA 17370; NRDC 104; Penick 1382;Penncapthrin; Pyresthrin; Resmethrin; SBP 1382; SBP 1383; Seco;[5-(Phenylmethyl)-3-furanyl]methyl2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate; dl-cis,trans-[(5-Benzyl-3-furyl)methyl]chrysanthemumate |
| Density: | 1.111g/cm3 |
| Melting Point: | 56.5℃ |
| Boiling Point: | 418.3oC at 760 mmHg |
| Flash Point: | 206.8oC |
| Solubility: | 0.038 mg l-1 (25 °C) |
| Hazard Symbols: | Xn,N |
| Risk Codes: | 22-50/53 |
| Safety: | Poison by ingestion, and intravenous routes. Moderately toxic by inhalation and skin contact. When heated to decomposition it emits acrid and irritating fumes. See also ESTERS. |
| PSA: | 39.44000 |
| LogP: | 5.15200 |
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Chemistry
Product Name: Resmethrin (CAS NO.10453-86-8)
Molecular Formula: C22H26O3
Molecular Weight: 338.44g/mol
Mol File: 10453-86-8 .mol
Einecs: 233-940-7
Appearance: Colorless crystals or waxy solid
Boiling point: 415.6 °C at 760 mmHg
Storage Temperature: 0-6°C
Flash Point: 205.2 °C
Density: 1.111 g/cm3
Water Solubility: Insoluble in water
Surface Tension: 43.9 dyne/cm
Enthalpy of Vaporization: 66.87 kJ/mol
Vapour Pressure: 4.07E-07 mmHg at 25°C
XLogP3-AA: 6.1
H-Bond Donor: 0
H-Bond Acceptor: 3
Product Categories: PyrethroidsAnalytical Standards; Alphabetic; Endocrine Disruptors (Draft)Pesticides; EPA; Insecticides; Method Specific; R; Alpha sort; PyrethroidsPesticides&Metabolites; Q-ZAnalytical Standards
Uses
Resmethrin (CAS NO.10453-86-8) has a strong contact action, pesticides are very efficient, the virulence of the housefly is 2.5 times higher than the pyrethrins; its virulence mosquito Culex pipiens than allethrin is about three times higher; it Blattella germanica poison force, more than tetramethrin is about 6 times higher. And its mammalian toxicity, lower than the pyrethrins. It is suitable for families, housing, warehouses and other sites of mosquitoes, flies, cockroaches and other pests prevention and treatment.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| bird - wild | LD50 | oral | 75mg/kg (75mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |
| dog | LC | inhalation | > 420mg/m3/4H (420mg/m3) | National Technical Information Service. Vol. AD747-345, | |
| dog | LDLo | intravenous | 250mg/kg (250mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | National Technical Information Service. Vol. AD747-345, |
| mammal (species unspecified) | LD50 | intraperitoneal | > 1gm/kg (1000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969. | |
| mammal (species unspecified) | LD50 | oral | > 3375mg/kg (3375mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969. | |
| mouse | LD50 | intraperitoneal | > 1gm/kg (1000mg/kg) | PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969. |
| mouse | LD50 | oral | 300mg/kg (300mg/kg) | Agricultural and Biological Chemistry. Vol. 37, Pg. 2681, 1973. | |
| mouse | LD50 | skin | > 5gm/kg (5000mg/kg) | Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969. | |
| mouse | LD50 | subcutaneous | > 2gm/kg (2000mg/kg) | Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969. | |
| rabbit | LD50 | skin | 2500mg/kg (2500mg/kg) | Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 9, 1978. | |
| rabbit | LDLo | intravenous | 250mg/kg (250mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: IRRITABILITY | National Technical Information Service. Vol. AD747-345, |
| rat | LC | inhalation | > 420mg/m3/4H (420mg/m3) | National Technical Information Service. Vol. AD747-345, | |
| rat | LD50 | oral | 1244mg/kg (1244mg/kg) | Fundamental and Applied Toxicology. Vol. 7, Pg. 299, 1986. | |
| rat | LD50 | skin | 3gm/kg (3000mg/kg) | Yakkyoku. Pharmacy. Vol. 38, Pg. 1331, 1987. | |
| rat | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969. | |
| rat | LDLo | intraperitoneal | 19200mg/kg (19200mg/kg) | National Technical Information Service. Vol. AD747-345, | |
| rat | LDLo | intravenous | 160mg/kg (160mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Biologico. Vol. 41, Pg. 283, 1975. |
Consensus Reports
EPA FIFRA 1988 pesticide subject to registration or re-registration. EPA Genetic Toxicology Program.
Safety Profile
Poison by ingestion, and intravenous routes. Moderately toxic by inhalation and skin contact. When heated to decomposition it emits acrid and irritating fumes. See also ESTERS.
Safety Information of Resmethrin (CAS NO.10453-86-8):
Hazard Codes: Xn
,N
Risk Statements: 22-50/53
22: Harmful if swallowed
50: Very Toxic to aquatic organisms
53: May cause long-term adverse effects in the aquatic environment
Safety Statements: 60/61-61-60
60: This material and/or its container must be disposed of as hazardous waste
61: Avoid release to the environment. Refer to special instructions safety data sheet
Specification
Resmethrin ,its CAS NO. is 10453-86-8 ,the synonyms is (5-(Phenylmethyl)-3-furanyl)methyl2,2-dimethyl-3-(2-methyl-1-propenyl)cyclop ; (5-(Phenylmethyl)-3-furanyl)methyl2,2-dimethyl-3-furylmethyl2,2-dimethyl-3)-2 ; (5-(Phenylmethyl)-3-furanyl)methylester ; (5-Benzyl-3-furyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate ; (5-Benzyl-3-furyl)methyl chrysanthemate ; (5-Benzyl-3-furyl)methyl(1rs)-cis,trans-2,2-dimethyl-3-(2-methylpropenyl)cyc ; (5-Benzyl-3-furyl)methyl-2,2-dimethyl-3-(2-methylpropenyl)-cyclopropanecarbo ; (5-Benzyl-3-furyl)methyl-2,2-dimethyl-3-(2-methylpropenyl)-cyclopropanecarboxy .