Basic Information | Post buying leads | Suppliers |
Name |
Rhodoquine |
EINECS | N/A |
CAS No. | 491-92-9 | Density | 1.0600 (rough estimate) |
PSA | 37.39000 | LogP | 4.23880 |
Solubility | N/A | Melting Point |
25°C |
Formula | C19H29N3O | Boiling Point | bp0.3 175-180°; bp1 182-194° |
Molecular Weight | 315.459 | Flash Point | N/A |
Transport Information | N/A | Appearance | N/A |
Safety | Human poison by an unspecified route. Experimental poison by ingestion, subcutaneous, intravenous, and intramuscular routes. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
PAMAQUINE;Plasmochin;Aminoquin;Prequine;Plasmoquine;Rhodoquine;Beprochine;Pamaquin;Praequine;Plasmocide; |
Product Name: 1-N,1-N-Diethyl-4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
Synonyms of Rhodoquine (CAS NO.491-92-9) : 1,4-Pentanediamine, N~1~,N~1~-diethyl-N~4~-(6-methoxy-8-quinolinyl)- ; 8-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methoxyquinoline ; N~1~,N~1~-Diethyl-N~4~-(6-methoxy-8-quinolinyl)-1,4-pentanediamine ; N1,N1-Diethyl-N5-(6-methoxy-8-quinolinyl)-1,4-pentanediamine ; Quinoline, 8-[[4- (diethylamino)-1-methylbutyl]amino]-6-methoxy-
CAS NO: 491-92-9
Molecular Formula:C19H29N3O
Molecular Weight :315.4531
Molecular Structure :
Index of Refraction:1.575
Surface Tension: 41.7 dyne/cm
Density: 1.051 g/cm3
Flash Point: 238.2 °C
Enthalpy of Vaporization: 73.28 kJ/mol
Boiling Point: 470.3 °C at 760 mmHg
Vapour Pressure: 5.13E-09 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
bird - domestic | LDLo | intramuscular | 33mg/kg (33mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. |
bird - domestic | LDLo | oral | 66mg/kg (66mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. |
cat | LDLo | intravenous | 5mg/kg (5mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. |
cat | LDLo | oral | 7500ug/kg (7.5mg/kg) | BEHAVIORAL: COMA BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. |
cat | LDLo | subcutaneous | 5mg/kg (5mg/kg) | BEHAVIORAL: COMA BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. |
chicken | LDLo | oral | 57mg/kg (57mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 201, Pg. 402, 1943. |
dog | LDLo | subcutaneous | 20mg/kg (20mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. | |
man | LDLo | unreported | 7353ug/kg (7.353mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
mouse | LD50 | oral | 68mg/kg (68mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 6, Pg. 185, 1951. | |
mouse | LDLo | subcutaneous | 12500ug/kg (12.5mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. |
rabbit | LDLo | intravenous | 3500ug/kg (3.5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. | |
rabbit | LDLo | oral | 220mg/kg (220mg/kg) | Rivista di Malariologia. Vol. 11, Pg. 3, 1932. | |
rabbit | LDLo | subcutaneous | 20mg/kg (20mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 144, Pg. 341, 1929. |
Human poison by an unspecified route. Experimental poison by ingestion, subcutaneous, intravenous, and intramuscular routes. When Rhodoquine (CAS NO.491-92-9) is heated to decomposition, it emits toxic fumes of NOx.