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Subtilisin

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  • Name Subtilisin
  • EINECS232-752-2
  • CAS No. 9014-01-1
  • Density1.3
  • PSA0.00000
  • LogP0.00000
  • Solubility100g/L at 25℃
  • Melting PointN/A
  • FormulaUnspecified
  • Boiling PointN/A
  • Molecular Weight0
  • Flash PointN/A
  • Transport InformationN/A
  • AppearanceN/A
  • Safety23-24-26-36/37/39-22-36/37-61-45-39
  • Risk Codes37/38-41-42-36/37/38-50-22
  • Molecular Structure
    Molecular Structure of 9014-01-1 (EC 3.4.21.14)
  • Hazard SymbolsXn,N
  • SynonymsXn,N

Subtilisin Synthetic route

2170-03-8

itaconic acid anhydride

subtilisin

subtilisin

vinylated subtilisin

vinylated subtilisin

Conditions
ConditionsYield
With sodium hydroxide In phosphate buffer for 0.5h; pH=7.8; Acylation;
subtilisin

subtilisin

1218-34-4

N-AcTrp

subtilisin imprinted with N-acetyl-L-tryptophan

subtilisin imprinted with N-acetyl-L-tryptophan

Conditions
ConditionsYield
In phosphate buffer at 0℃; for 0.5h; pH=7.8; Substitution;
subtilisin

subtilisin

2280-01-5

N-acetyl-D-tryptophan

subtilisin imprinted with N-acetyl-D-tryptophan

subtilisin imprinted with N-acetyl-D-tryptophan

Conditions
ConditionsYield
In phosphate buffer at 0℃; for 0.5h; pH=7.8; Substitution;

Subtilisin Consensus Reports

Reported in EPA TSCA Inventory.

Subtilisin Standards and Recommendations

ACGIH TLV: CL 0.00006 mg/m3

Subtilisin Specification

The Subtilisin, with the CAS registry number 9014-01-1,is also known as Bacillopeptidase A. It belongs to the product categories of Hydrolases;Specialty Enzymes.Its EINECS number is 232-752-2. What's more,Its systematic name is Subtilisin.It is a serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.It can be produced by submerged fermentation of Bacillus licheniformis (Baeillus licheni formis).

Safety Information of Subtilisin:
The Subtilisin is risk of serious damage to eyes,and irritating to eyes, respiratory system and skin .It may cause sensitization by inhalation,so do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.When you use it,wear suitable protective clothing, gloves and eye/face protection.And avoid comtact with skin.

Uses of Subtilisin:
The Subtilisin can be used as proteolytic enzymes.And it is mainly used for gelatin production, and can significantly reduce the extraction time. It is also used in vegetable protein, animal protein and fish protein hydrolysis.Besides,a commercial raw proteolytic enzyme used in laundry detergents.
 

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