- Sulfapyridine
- Sulfapyridine sodium
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Cas Database |
| Name |
Sulfapyridine sodium |
EINECS | 204-850-5 |
| CAS No. | 127-57-1 | Density | N/A |
| PSA | N/A | LogP | N/A |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C11H11 N3 O2 S . Na | Boiling Point | 473.5oC at 760 mmHg |
| Molecular Weight | 271.275 | Flash Point | 240.2oC |
| Transport Information | N/A | Appearance | N/A |
| Safety | Moderately toxic by ingestion, intraperitoneal, subcutaneous, intravenous, and parenteral routes. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols |
|
| Synonyms |
Izopiridina;Benzenesulfonamide,4-amino-N-2-pyridinyl-, monosodium salt (9CI);Sodium, (N1-2-pyridylsulfanilamido)-(7CI);Sulfanilamide, N1-2-pyridyl-, monosodium salt (8CI);Sulfapyridine sodium;Sulfapyridinesodium deriv (6CI);2-Sulfanilamidopyridine sodium salt;Sodiumsulfapyridine;Soludagenan; |
Article Data | 1 |
Sulfapyridine sodium Chemical Properties
Product Name: Sulfapyridine sodium (CAS NO.127-57-1)
Molecular Formula: C11H10N3O2S•Na
Molecular Weight: 271.29g/mol
Mol File: 127-57-1.mol
Boiling point: 473.5 °C at 760 mmHg
Flash Point: 240.2 °C
Enthalpy of Vaporization: 73.67 kJ/mol
Vapour Pressure: 3.9E-09 mmHg at 25°C
H-Bond Donor: 1
H-Bond Acceptor: 5
Structure Descriptors of Sulfapyridine sodium (CAS NO.127-57-1):
IUPAC Name: sodium (4-aminophenyl)sulfonyl-pyridin-2-ylazanide
Canonical SMILES: C1=CC=NC(=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Na+]
InChI: InChI=1S/C11H10N3O2S.Na/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11;/h1-8H,12H2;/q-1;+1
InChIKey: DAINBAXHBFSNCQ-UHFFFAOYSA-N
Sulfapyridine sodium Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intravenous | 693mg/kg (693mg/kg) | Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940. | |
| monkey | LDLo | intravenous | 600mg/kg (600mg/kg) | Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940. | |
| mouse | LD50 | intramuscular | 1096mg/kg (1096mg/kg) | Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940. | |
| mouse | LD50 | intraperitoneal | 910mg/kg (910mg/kg) | Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940. | |
| mouse | LD50 | intravenous | 696mg/kg (696mg/kg) | Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940. | |
| mouse | LD50 | oral | 2gm/kg (2000mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 68, Pg. 259, 1940. | |
| mouse | LD50 | parenteral | 1gm/kg (1000mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 328, 1940. | |
| mouse | LD50 | subcutaneous | 872mg/kg (872mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 71, Pg. 138, 1941. | |
| rat | LD50 | intravenous | 648mg/kg (648mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 33, Pg. 80, 1944. | |
| rat | LD50 | oral | 2994mg/kg (2994mg/kg) | Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940. | |
| rat | LDLo | intraperitoneal | 1120mg/kg (1120mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 15, 1940. |
Sulfapyridine sodium Consensus Reports
Reported in EPA TSCA Inventory.
Sulfapyridine sodium Safety Profile
Moderately toxic by ingestion, intraperitoneal, subcutaneous, intravenous, and parenteral routes. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx.
Sulfapyridine sodium Specification
Sulfapyridine sodium ,its CAS NO. is 127-57-1,the synonyms is EINECS 204-850-5 ; N(sup 1)-2-Pyridylsulfanilamide sodium salt ; Sodium sulfapymonohydrate ; Sodium sulfapyridine ; Sodium sulphapyridine ; Soluble sulfapyridine ; Soludagenan ; Sulfanilamide, N(sup 1)-2-pyridyl-, N(sup 1)-sodium deriv. ; Sulfanilamide, N(sup 1)-2-pyridyl-, monosodium salt ; Sulfapyridine, sodium salt ; UNII-H3SKB3662O ; Benzenesulfonamide, 4-amino-N-2-pyridinyl-, monosodium salt ; Benzenesulfonamide, 4-amino-N-2-pyridinyl-, sodium salt (1:1) .
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