The Benzenesulfonamide,4-amino-N-2-thiazolyl-, with the CAS registry number 72-14-0, is also known as 2-(p-Aminobenzenesulfonamido)thiazole. It belongs to the product categories of Aromatics; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur & Selenium Compounds. Its EINECS number is 200-771-5. This chemical's molecular formula is C₉H₉N₃O₂S₂ and molecular weight is 255.32. What's more, its systematic name is 4-Amino-N-(1,3-thiazol-2-yl)benzenesulfonamide. Its classification codes are: (1)Anti-Infective Agents; (2)Antibacterial; (3)Human Data; (4)Mutation data; (5)Reproductive Effect; (6)Tumor data. It should be sealed and stored in a cool and dry place. Moreover, it should be protected from light. This chemical is mainly used to cure infectious diseases such as hemolytic streptococcus, meningococci and pneumonia. It is also used in biochemical research. It is an organosulfur compound that has been used as a short-acting sulfa drug. It once was a common oral and topical antimicrobial until less toxic alternatives were discovered.

Physical properties of Benzenesulfonamide,4-amino-N-2-thiazolyl- are: (1)ACD/LogP: 0.05; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.04; (4)ACD/LogD (pH 7.4): -0.34; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 24.90; (8)ACD/KOC (pH 7.4): 10.46; (9)#H bond acceptors: 5; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 121.7 Å²; (13)Index of Refraction: 1.704; (14)Molar Refractivity: 63.489 cm³; (15)Molar Volume: 163.535 cm³; (16)Polarizability: 25.169×10^-24cm³; (17)Surface Tension: 83.0879974365234 dyne/cm; (18)Density: 1.561 g/cm³; (19)Flash Point: 243.799 °C; (20)Enthalpy of Vaporization: 74.383 kJ/mol; (21)Boiling Point: 479.509 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

Preparation: this chemical can be prepared by (4-thiazol-2-ylsulfamoyl-phenyl)-carbamic acid methyl ester by heating. This reaction will need reagent calcium hydroxide and solvent H₂O with the reaction time of 2 hours. The yield is about 74.5%.

Uses of Benzenesulfonamide,4-amino-N-2-thiazolyl-: it can be used to produce N-(4-thiazol-2-ylsulfamoyl-phenyl)-succinamic acid. It will need solvent acetone. The yield is about 73%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: O=S(=O)(Nc1nccs1)c2ccc(N)cc2
(2)Std. InChI: InChI=1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)
(3)Std. InChIKey: JNMRHUJNCSQMMB-UHFFFAOYSA-N

The toxicity data is as follows: