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TETRAMETHYLTHIOUREA

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TETRAMETHYLTHIOUREA

EINECS 220-488-0
CAS No. 2782-91-4 Density 1.013 g/cm3
PSA 38.57000 LogP 0.39450
Solubility soluble in water Melting Point 75-77 °C(lit.)
Formula C5H12N2S Boiling Point 245 °C at 760 mmHg
Molecular Weight 132.23 Flash Point 102 °C
Transport Information N/A Appearance White crystals
Safety 22-24/25-36 Risk Codes 22-20/21/22
Molecular Structure Molecular Structure of 2782-91-4 (Tetramethylthiourea) Hazard Symbols HarmfulXn
Synonyms

Thiourea,tetramethyl- (9CI);Urea, 1,1,3,3-tetramethyl-2-thio- (6CI,8CI);1,1,3,3-Tetramethyl-2-thiourea;Basthioryl;N,N,N',N'-Tetramethylthiourea;NSC102499;

Article Data 43

TETRAMETHYLTHIOUREA Chemical Properties

IUPAC Name:1,1,3,3-Tetramethylthiourea (2782-91-4)
Synonyms:Tetramethylthiourea ; 1,1,3,3-Tetramethyl-2-thiourea ; 1,1,3,3-Tetramethylthiourea ; ((Ch3)2n)2cs ; 1,1,3,3-Tetramethyl-2-thio-ure ; Basthioryl ; N,N,N',N'-Tetramethylthiourea ; N,N,N’,N’-Tetramethylthioharnstoff
CAS: 2782-91-4
MF: C5H12N2S
MW: 132.23
MS:
EINECS: 220-488-0
Product Categories: Heterocycles;Organic Building Blocks;Sulfur Compounds;Thioureas
Mol File: 2782-91-4.mol
Surface Tension: 40.3 dyne/cm 
Density: 1.012 g/cm3 
Flash Point: 102 °C
Melting point:  75-77 °C(lit.) 
Enthalpy of Vaporization: 48.21 kJ/mol 
Boiling Point: 245 °C at 760 mmHg 
Vapour Pressure: 0.0294 mmHg at 25°C 
Water Solubility:  32 g/L (20 ºC)
BRN : 1744916
Appearance:  Tetramethylthiourea (2782-91-4) is colorless to yellow crystalline chunks ,white crystals.

TETRAMETHYLTHIOUREA Uses

Tetramethylthiourea (2782-91-4) is used in organic synthesis.

TETRAMETHYLTHIOUREA Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 unreported 400mg/kg (400mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 17(3), Pg. 32, 1973.
mouse LDLo oral 500mg/kg (500mg/kg)   Teratology, The International Journal of Abnormal Development. Vol. 23, Pg. 335, 1981.
rat LD50 oral 920mg/kg (920mg/kg)   Journal of Environmental Pathology and Toxicology. Vol. 2, Pg. 889, 1979.

TETRAMETHYLTHIOUREA Safety Profile

Hazard Codes : Xn
Risk Statements : 20/21/22
20/21/22:  Harmful by inhalation, in contact with skin and if swallowed
Safety Statements : 22-24/25-36
22:  Do not breathe dust
36:  Wear suitable protective clothing
24/25:  Avoid contact Tetramethylthiourea (2782-91-4) with skin and eyes 
WGK Germany:  3
RTECS:  YU2750000
HS Code:  29309070

TETRAMETHYLTHIOUREA Specification

1.Air & Water Reactions:Tetramethylthiourea (2782-91-4) is water soluble.
2.Reactivity Profile: An organosulfide amide. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
3.Fire Hazard: Flash point data for Tetramethylthiourea are not available, but Tetramethylthiourea is probably combustible.
 

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