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Cas Database |
| Name |
TRIFLUPROMAZINE |
EINECS | N/A |
| CAS No. | 146-54-3 | Density | 1.238g/cm3 |
| PSA | 31.78000 | LogP | 5.32480 |
| Solubility | 1.762mg/L(24 oC) | Melting Point |
25°C |
| Formula | C18H19 F3 N2 S | Boiling Point | 427.6°Cat760mmHg |
| Molecular Weight | 352.423 | Flash Point | 212.4°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of F−, NOx, and SOx. See also FLUORIDES. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Phenothiazine,10-[3-(dimethylamino)propyl]-2-(trifluoromethyl)- (6CI,8CI); 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine;2-(Trifluoromethyl)promazine; Fluopromazine; Psyquil; Siquil; Trifluopromazine;Triflupromazine |
Article Data | 11 |
TRIFLUPROMAZINE Chemical Properties
Product Name: Triflupromazine (CAS NO.146-54-3)
Molecular Formula: C18H19F3N2S
Molecular Weight: 352.4170696g/mol
Mol File: 146-54-3.mol
Einecs: 205-673-6
Boiling point: 427.6 °C at 760 mmHg
Flash Point: 212.4 °C
Density: 1.238 g/cm3
Surface Tension: 39.1 dyne/cm
Enthalpy of Vaporization: 68.26 kJ/mol
Vapour Pressure: 1.62E-07 mmHg at 25°C
XLogP3-AA: 5.2
H-Bond Donor: 0
H-Bond Acceptor: 5
TRIFLUPROMAZINE Toxicity Data With Reference
| 1. | dlt-mus-ipr 25 mg/kg | MUREAV Mutation Research. 17 (1973),87. | ||
| 2. | cyt-mam:kdy 10 mg/L/8H-C | FCTXAV Food and Cosmetics Toxicology. 8 (1970),617. | ||
| 3. | orl-rat LD50:185 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 36 (1986),797. | ||
| 4. | ipr-rat LD50:94 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 2 (1960),540. | ||
| 5. | orl-mus LD50:245 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 2 (1960),540. | ||
| 6. | ipr-mus LD50:100 mg/kg | MUREAV Mutation Research. 17 (1973),87. | ||
| 7. | ivn-mus LD50:44 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 2 (1960),540. |
TRIFLUPROMAZINE Consensus Reports
EPA Genetic Toxicology Program.
TRIFLUPROMAZINE Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of F−, NOx, and SOx. See also FLUORIDES.
TRIFLUPROMAZINE Specification
Triflupromazine ,its CAS NO. is 146-54-3,the synonyms is Dimethyl(3-(2-trifluoromethylphenothiazin-10-yl)propyl)amine ; Fluopromazine ; Triflupromazine ; Trifluoropromazine ; 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)-10h-phenothiazine ; Trifluopromazine ; Vetame .
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