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Chemical Baike

Activation of Carboxylic Acid Group

Activate the carboxylic acid group of the crown ether aminocarboxylic acid monomer. This can be done using coupling reagents such as DCC (dicyclohexylcarbodiimide) or HATU (1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxide hexafluorophosphate) along with a suitable base.

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