Asymmetric 1,4-addition refers to the addition of an organozinc compound to a specific position (the 1,4-position) on a molecule, resulting in the formation of a new chiral center with high enantioselectivity. Asymmetric reactions are crucial in organic synthesis to create molecules with defined chirality, which is important in fields like pharmaceuticals.
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Hexanal, 3-ethyl-5-oxo- (9CI)
(E)-benzyl 4-oxo-2-(pent-1-enyl)piperidine-1-carboxylate
(R)-3-(4-benzyloxylphenyl)-3-methylcyclohexanone
tert-butyl (2R,4R)-5,5-diphenyl-4-(pyrrolidine-1-carbonyl)pyrrolidine-2-carboxylate
