The key step in this reaction is the asymmetric alkylation of the enolates. Alkylation involves the introduction of an alkyl group onto the enolate carbon atom. This reaction is highly stereoselective, meaning that it favors the formation of one enantiomer over the other. The choice of chiral reagents or catalysts plays a crucial role in controlling the stereochemistry of the newly formed chiral center.
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ethyl α-methyl-α-benzylacetoacetate
