Charge

The presence of positively charged amino groups in PAAs may allow them to interact with negatively charged regions of calcium channel proteins.

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Structure-activity relationships of polycyclic aromatic amines with calcium channel blocking activity
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Stereochemistry Nuclear magnetic resonance (NMR) spectroscopy Substituents Peptide Synthesis Steric Effects Aromatic Rings Ring Size Hydrophobicity/Hydrophilicity Chain Length Metal Center Circular Dichroism (CD) Spectroscopy Isothermal titration calorimetry (ITC)

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