Click chemistry involves reactions that are high-yielding, wide in scope, and selective under mild conditions. Perform the click reaction under mechanochemical conditions, which involve using mechanical force to drive chemical reactions. This can be achieved using a ball mill or other milling devices. The click reaction could involve the reaction between azide and alkyne functional groups, forming the thiourea linkage.
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Urea, N,N''-(1,2-phenylene)bis[N'-phenyl-
