The conformational preferences of the bicyclo[n.1.0] system also affect the regioselectivity. Different conformations can present different reactivity patterns, making one position more favorable for attack compared to others.
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Cyclohexene, 3-(bromomethyl)-3,5,5-trimethyl-1-(2,2,2-trichloroethyl)-
D-Proline, N-acetyl-L-valyl-2-methyl-4-methylene-, pentafluorophenyl ester
1,2,4-trimethyl-4-(prop-1-en-2-yl)cyclohexene
