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DNA-Binding Properties

Some metal complexes, including diorganotin complexes, can interact with DNA. This DNA binding may have implications for their cytotoxicity and anticancer properties. When a complex binds to DNA, it can interfere with DNA replication and transcription, which can be a mechanism for their cytotoxic effects. Understanding the DNA-binding properties of these complexes is crucial for elucidating their potential as anticancer agents.

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