Gas evolution

The release of gaseous byproducts (e.g., CHCl?, CHF?) during a reaction, detectable by bubbling or mass spectrometry.

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Elemental analysis Asymmetric synthesis Regioselectivity Diastereoselectivity Green chemistry Solid-phase synthesis Microwave-assisted synthesis Column chromatography NMR spectroscopy Distillation Catalyst Thin-layer chromatography (TLC) Ligand Molecular docking Stereochemistry Lead compound Enantioselectivity Steric hindrance Enantiomeric excess (ee) Recrystallization Mass spectrometry (MS) Nucleophilic substitution Differential scanning calorimetry (DSC) Atom economy Pharmacophore one-pot synthesis Kinetics High-performance liquid chromatography (HPLC) Infrared spectroscopy (IR) Electrochemistry Deprotection Filtration Solvent polarity TLC (thin-layer chromatography) Protecting group Nuclear Magnetic Resonance (NMR) Resolution X-ray crystallography Leaving group Density functional theory (DFT) Enzyme inhibition High-Throughput Screening Scale-up Steric Effects Chemoselectivity Nucleophilic Attack Reaction Mechanism Electronic effects UV-Vis Spectroscopy Cyclic Voltammetry (CV)

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