Azetidinic amino acids are often designed to interact with glutamate receptors, which are integral to excitatory neurotransmission. This includes receptors such as AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) and NMDA (N-methyl-D-aspartate) receptors. Pharmacological studies aim to understand the binding affinity, selectivity, and functional effects of these compounds on different glutamate receptor subtypes.
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