Oxidation of the Hydroxyl Group

The hydroxyl group can be oxidized to the formyl group (aldehyde) to obtain the α-substituted β-formyl δ-lactone.

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Asymmetric synthesis of α-substituted β-formyl δ-lactones via a Michael addition/α-alkylation protocol
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DE NOVO-SYNTHESIS OF CARBOHYDRATES- PREPARATION OF 4-AMINO-4-DEOXY-D,L-RIBOSE DERIVATIVES
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Characterization Deprotection Michael addition Purification Stereochemistry Control Amination Protection of Hydroxyl Groups α-Alkylation Introduction of Amino Group

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