The reaction to synthesize pyrimidine derivatives typically involves the reaction of benzoyl isothiocyanate with compounds containing active methylene groups. In this case, the reaction proceeds through the formation of a thiourea intermediate, which reacts with the active methylene compound to yield pyrimidine derivatives.
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3-Benzoylamino-2-cyano-3-thioxopropionamide
2-Pyrimidinamine, N-methyl-4,6-diphenyl-
4-CHLORO-5-IODO-6-METHYLPYRIMIDINE
ethyl 4-methyl-6-(methylthio)-2-phenylpyrimidine-5-carboxylate
