Researchers have been actively exploring small-molecule compounds that can interfere with TLR3 activation. These compounds are designed to target various components of the TLR3 signaling pathway. For instance, some compounds have been found to inhibit the dimerization of TLR3, which is necessary for its activation.
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2-[[(2-FLUOROPHENYL)SULFONYL]AMINO]-3-PHENYLPROPANOIC ACID
(3-{4-[5-(2,3-dichloro-phenyl)-2-methyl-2H-pyrazol-3-yl]-piperidine-1-sulfonylamino}-propyl)-carbamic acid tert-butyl ester
4-METHOXY-N-2-NAPHTHALENYL-BENZAMIDE
