Synthesis of Key Fragments

Synthesize the critical fragments or building blocks of the target molecule. These could be complex intermediates or simpler starting materials.

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Total synthesis of amphidinolide E and amphidinolide E stereoisomers
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Biomimetic three-component assembly of the central core of halichonadins K and L
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Characterization Protecting groups Dimeric Cascade reactions Isolation and Purification Retrosynthetic analysis Purification and characterization Stereochemistry Control Optimization and Scale-Up Final assembly Design and Retrosynthetic Analysis Macrocyclization Functional Group Manipulations Bioactivity Testing Identification of Key Fragments

Chemical Baike