The chiral organolithium intermediate obtained from the asymmetric bromine-lithium exchange can be used as a key building block in the synthesis of natural products. These intermediates can be manipulated further to construct complex molecules with specific stereochemistry, as required for natural product synthesis.
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2,2',4,4',6,6'-HEXABROMOBIPHENYL
compound 3
Phentydrone
(S)-1-Phenylsulfonyl-5-(tetrahydropyranyloxy)hexane
