One way to synthesize the quinoline ring is through a Pictet-Spengler reaction. You could start with an appropriate substituted aromatic amine and an aldehyde. Protect any functional groups that might be sensitive to the reaction conditions. Perform the Pictet-Spengler reaction to form the quinoline ring.
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[2aS,3R,6R(1S,2R),7aS,7bR]-hexahydro-2,2-bis(1-methylethyl)-3-ethenyl-6-[(2-phenylcyclohexyl)oxy]-2H-1,4,5-trioxy-4a-aza-2-silacyclopent[cd]indene
2-(3-hydroxyimino-2,3-dihydroimidazo[1,2-a]pyridin-2-yliden)-2-phenylacetonitrile
