If the reaction involves an aniline with two substituents (R1 and R2) on the aromatic ring, it can result in the formation of triamines. This occurs because the Mannich reaction can add three amino groups to the molecule.
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(R)-tert-butyl 3-hydroxy-2-oxo-3-[(S)-2-oxocyclohexyl]indolin-2-one-1-carboxylate
