2-Methoxyestradiol (2-ME) is known to inhibit tubulin polymerization, which is essential for cell division. The tubulin protein forms microtubules that are crucial for mitosis. Inhibition of tubulin polymerization can lead to cell cycle arrest and cell death in rapidly dividing cells, such as cancer cells.
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3-O-(tert-butyl)dimethylsilyl-2-methoxy-17-(1-phenyl-1H-1,2,3-triazol-4-yl)estradiol
Cyclohexanone
hexane
