- 687-69-4Alanylglycine
- 6877-32-3Corynoxan-16-carboxylicacid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (16E)-
- 68774-77-61,2,4-Triazolo[4,3-a]pyrazine,8-chloro-
- 68774-79-81,2,4-Triazolo[4,3-apyrazin-8-amine
- 68776-57-83-Isoxazolecarbonitrile
- 68776-58-94-Isoxazolecarbonitrile
- 68776-59-05-cyanoisoxazole
- 68776-61-4OXAZOLE-5-CARBONITRILE
- 68776-62-54-Pyridazinecarbonitrile
- 68776-86-3Heptanoic acid,2-acetyl-, methyl ester
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
| Name |
Triaziquone |
EINECS | N/A |
| CAS No. | 68-76-8 | Density | 1.727g/cm3 |
| PSA | 43.17000 | LogP | -1.00580 |
| Solubility | N/A | Melting Point |
162.5-163° |
| Formula | C12H13 N3 O2 | Boiling Point | 376.5°C at 760 mmHg |
| Molecular Weight | 231.254 | Flash Point | 175.1°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intraperitoneal, intravenous, and parenteral routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. Used as a drug for the treatment of neoplastic diseases. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
2,5-Cyclohexadiene-1,4-dione,2,3,5-tris(1-aziridinyl)- (9CI); p-Benzoquinone, 2,3,5-tris(1-aziridinyl)- (8CI);p-Benzoquinone, tris(1-aziridinyl)- (6CI); 10257RP;2,3,5-Ethylenimine-1,4-benzoquinone; 2,3,5-Triethyleneimino-p-benzoquinone;2,3,5-Tris(aziridinyl)-1,4-benzoquinone;2,3,5-Tris(ethylenimino)-1,4-benzoquinone; 2,3,5-Tris(ethylenimino)-p-benzoquinone;2,3,5-Trisethyleneiminobenzoquinone; A 163; BAY 3231; NSC-29215; Oncoredox;Oncovedex; Prenimon; Riker 601; TEIB; Trenimon; Treninon; Triaziquinone;Triaziquinonum; Triaziquon; Triaziquone; Triethyleneiminobenzoquinone;Triethyleniminobenzoquinone; Tris(1-aziridinyl)-p-benzoquinone;Tris(aziridinyl)-p-benzoquinone; Tris(ethyleneimino)benzoquinone;Trisethyleneiminoquinone |
Triaziquone Synthetic route
- 151-56-4
ethyleneimine
- 530-55-2
2,6-dimethoxy-p-quinone
A
- 5677-51-0
2,6-bis-aziridin-1-yl-hydroquinone
B
- 68-76-8
triaziquone
| Conditions | Yield |
|---|---|
| With methanol |
Triaziquone Chemical Properties
EINECS: 200-692-6
Empirical Formula: C12H13N3O2
Molecular Weight: 231.2505 g/mol
Index of Refraction: 1.846
Density: 1.727 g/cm3
Flash Point: 175.1 °C
Enthalpy of Vaporization: 62.42 kJ/mol
Boiling Point: 376.5 °C at 760 mmHg
Vapour Pressure: 7.19E-06 mmHg at 25 °C
Solubility: Slightly soluble in water
Appearance: Purple needle-like crystals
Structure of Triaziquone (CAS NO.68-76-8):
IUPAC Name: 2,3,5-Tris(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione
Canonical SMILES: C1CN1C2=CC(=O)C(=C(C2=O)N3CC3)N4CC4
InChI: InChI=1S/C12H13N3O2/c16-9-7-8(13-1-2-13)12(17)11(15-5-6-15)10(9)14-3-4-14/h7H,1-6H2
InChIKey: PXSOHRWMIRDKMP-UHFFFAOYSA-N
Triaziquone Uses
Triaziquone (CAS NO.68-76-8) can be used as a drug for the treatment of neoplastic diseases.
Triaziquone Toxicity Data With Reference
| 1. | sln-dmg-orl 50,000 ppm | MUREAV Mutation Research. 2 (1965),29. | ||
| 2. | cyt-hmn:lym 50 nmol/L | MUREAV Mutation Research. 149 (1985),83. | ||
| 3. | ipr-rat LD50:500 µg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 16 (1966),1533. | ||
| 4. | ivn-rat LD50:500 µg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 20 (1970),1467. | ||
| 5. | par-rat LD50:500 µg/kg | RRCRBU Recent Results in Cancer Research. 52 (1975),76. |
Triaziquone Consensus Reports
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 367.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 ,1975,p. 67.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 ,1975,p. 67.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Community Right-To-Know List. EPA Genetic Toxicology Program.
Triaziquone Safety Profile
Poison by intraperitoneal, intravenous, and parenteral routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Human mutation data reported. When heated to decomposition Triaziquone (CAS NO.68-76-8) emits toxic fumes of NOx.
Triaziquone Specification
Triaziquone , its cas register number is 68-76-8. It also can be called 2,3,5-Tris(ethyleneimino)benzoquinone ; Tris(1-aziridinyl)-p-benzoquinone ; 2,5-Cyclohexadiene-1,4-dione, 2,3,5-tris(1-aziridinyl)- ; and 2,3,5-Tri(1-aziridinyl)benzo-1,4-quinone . It is an amine , and amines are chemical bases. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Triaziquone (CAS NO.68-76-8) is probably combustible.
What can I do for you?
Get Best Price
