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Trimethoxazine

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Name

Trimethoxazine

EINECS N/A
CAS No. 635-41-6 Density 1.184g/cm3
PSA 57.23000 LogP 1.12270
Solubility N/A Melting Point 120-122°
Formula C14H19 N O5 Boiling Point 461.5°C at 760 mmHg
Molecular Weight 281.309 Flash Point 232.9°C
Transport Information N/A Appearance N/A
Safety Moderately toxic by ingestion, intraperitoneal, subcutaneous, parenteral, and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 635-41-6 (trimetozine) Hazard Symbols N/A
Synonyms

Morpholine,4-(3,4,5-trimethoxybenzoyl)- (6CI,7CI,8CI,9CI);4-(3,4,5-Trimethoxybenzoyl)morpholine; 4-(3,4,5-Trimethoxybenzoyl)tetrahydro-1,4-oxazine;Abbott 22370; N-(3,4,5-Trimethoxybenzoyl)tetrahydro-1,4-oxazine; NSC 62939;Opalene; PS 2383; Sedoxazine; Trifenoxazin; Trimethoxazine; Trimetozin;Trimetozine; Trioxazin; Trioxazine; V 7

Article Data 16

Trimethoxazine Chemical Properties

Product Name: Trimethoxazine
Synonyms of Trimethoxazine (CAS NO.635-41-6) : 4-[(3,4,5-Trimethoxyphenyl)carbonyl]morpholine ; Methanone, 4-morpholinyl(3,4,5-trimethoxyphenyl)- ; Morpholin-4-yl(3,4,5-trimethoxyphenyl)methanone ; N-(3,4,5-Trimethoxybenzoyl)-morpholino ; 3,4,5-Trimethoxybenzoyl-N-tetrahydroxazine
InChI: InChI=1/C14H19NO5/c1-17-11-8-10(9-12(18-2)13(11)19-3)14(16)15-4-6-20-7-5-15/h8-9H,4-7H2,1-3H3
CAS NO:635-41-6
Molecular Formula:C14H19NO5
Molecular Weight :281.3044
Molecular Structure :
EINECS: 211-236-0
Index of Refraction: 1.529
Surface Tension: 41.2 dyne/cm
Density: 1.184 g/cm3
Flash Point: 232.9 °C
Enthalpy of Vaporization: 72.23 kJ/mol
Boiling Point: 461.5 °C at 760 mmHg
Vapour Pressure: 1.07E-08 mmHg at 25°C

Trimethoxazine Uses

 Trimethoxazine (CAS NO.635-41-6) is used as tranquilizers and sedatives, can relieve tension and anxiety.

Trimethoxazine Toxicity Data With Reference

1.    

orl-rat LD50:1800 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 21 (1971),719.
2.    

ipr-rat LD50:1080 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 4 (1976),2487.
3.    

scu-rat LD50:1400 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 4 (1976),2487.
4.    

orl-mus LD50:2400 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 4 (1976),2487.
5.    

ipr-mus LD50:1150 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 4 (1976),2487.
6.    

scu-mus LD50:1550 mg/kg

    THERAP    Therapie. 20 (1965),401.
7.    

ivn-mus LD50:960 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,312.
8.    

par-mus LD50:1200 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 33 (1970),70.

Trimethoxazine Safety Profile

Moderately toxic by ingestion, intraperitoneal, subcutaneous, parenteral, and intravenous routes. An experimental teratogen. Experimental reproductive effects. When Trimethoxazine (CAS NO.635-41-6) is heated to decomposition, it emits toxic fumes of NOx.

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