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EINECS 300-006-3
CAS No. 38748-32-2 Density 1.48 g/cm3
PSA 84.12000 LogP 1.10310
Solubility soluble in DMSO Melting Point 226-227 °C
Formula C20H24O6 Boiling Point 601.7 °C at 760 mmHg
Molecular Weight 360.407 Flash Point 220.7 °C
Transport Information N/A Appearance White crystalline solid
Safety 22-24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 38748-32-2 (Triptolide) Hazard Symbols N/A

(-)-Triptolide;NSC 163062;PG 490;[3bS-(3ba,4aa,5aR*,6b,6ab,7ab,7ba,8aR*,8bb)]-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one;

Article Data 9

Triptolide Chemical Properties

Name : Triptolide 

Molecular Structure :  

Molecular Formula : C20H24O6
Molecular Weight : 360.41
CAS Registry Number : 38748-32-2
storage temp : 2-8°C
form : solid
solubility :soluble
color :white to off-white
Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease Triptolide is a potent, biologically active compound isolated from the medicinal 'Thunder God Vine' Tripterygium wilfordii Hook F. The TCM tea Lei Gong Teng made from this plant has been used for centuries, as a therapeutic against cancer, inflammation, and auto-immune diseases. Crews and colleagues showed that triptolide causes cell growth arrest in certain cell types.

Triptolide Uses

Diterpenoid triepoxide with immunosuppressant
antitumor properties

Triptolide Toxicity Data With Reference


ipr-mus LD50:900 µg/kg

   CYLPDN    Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.

ivn-mus LD50:800 µg/kg

   CYLPDN    Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.

ivn-dog LDLo:160 µg/kg

   CYLPDN    Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.

Triptolide Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.
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