The CAS registry number of Yohimbine is 146-48-5. Its EINECS registry number is 205-672-0. The systematic name is methyl (16α,17α)-17-hydroxyyohimban-16-carboxylate. In addition, the molecular formula is C₂₁H₂₆N₂O₃ and the molecular weight is 354.44. What's more, it is an alkaloid with stimulant and aphrodisiac effects found naturally in Pausinystalia yohimbe and belongs to the classes of Adrenoceptor and API.

Physical properties about this chemical are: (1)ACD/LogP: 2.20; (2)ACD/LogD (pH 5.5): -0.56; (3)ACD/LogD (pH 7.4): 1.05; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1.95; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 26.39; (8)#H bond acceptors: 5; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 3; (11)Polar Surface Area: 43.7 Å²; (12)Index of Refraction: 1.66; (13)Molar Refractivity: 99.46 cm³; (14)Molar Volume: 269.1 cm³; (15)Polarizability: 39.42 ×10^-24cm³; (16)Surface Tension: 63.3 dyne/cm; (17)Density: 1.31 g/cm³; (18)Flash Point: 282.2 °C; (19)Enthalpy of Vaporization: 86.43 kJ/mol; (20)Boiling Point: 543 °C at 760 mmHg; (21)Vapour Pressure: 1.27E-12 mmHg at 25°C.

Preparation of Yohimbine: it can be prepared by yohimbinone. The other product is (+/-)-b-yohimbine. This reaction will need reagent sodium borohydride and solvent methanol. The reaction time is 20 minutes at reaction temperature of 0 °C. The yield is about 52.9%.

Uses of Yohimbine: it has been used to facilitate recall of traumatic memories in the treatment of posttraumatic stress disorder. And it can be used in arteriosclerosis and angina pectoris, and has been used as a local anesthetic and mydriatic and for its purported aphrodisiac properties. In addition, it can be used as both an over-the-counter dietary supplement in herbal extract form and prescription medicine in pure form for the treatment of sexual dysfunction.

When you are using this chemical, please be cautious about it as the following:
This chemical is toxic by inhalation, in contact with skin and if swallowed. And it has danger of very serious irreversible effects. During using it, wear suitable protective clothing, gloves and eye/face protection. And in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.). In addition, you should take off immediately all contaminated clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(OC)[C@@H]5[C@H]4C[C@H]3c2nc1ccccc1c2CCN3C[C@@H]4CC[C@@H]5O
(2)InChI: InChI=1/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1
(3)InChIKey: BLGXFZZNTVWLAY-SCYLSFHTBA

The toxicity data is as follows: