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| CAS No.: | 1024-57-3 |
|---|---|
| Name: | Epoxyheptachlor |
| Molecular Structure: | |
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| Formula: | C10H5 Cl7 O |
| Molecular Weight: | 389.32 |
| Synonyms: | 2,5-Methano-2H-indeno[1,2-b]oxirene,2,3,4,5,6,7,7-heptachloro-1a,1b,5,5a,6,6a-hexahydro-, (1aa,1bb,2a,5a,5ab,6b,6aa)-;4,7-Methanoindan,1,4,5,6,7,8,8-heptachloro-2,3-epoxy-3a,4,7,7a-tetrahydro- (8CI);(?à)-cis-Heptachlor epoxide;ENT25584;Epoxyheptachlor;GPKh epoxide;HCE;HE;Hepox;Heptachlor cis-oxide;Heptachlor epoxide;Heptachlor epoxide B;Heptachlor exo-epoxide;Heptepoxide;Velsicol 53CS17;cis-Heptachlor epoxide; |
| EINECS: | 213-831-0 |
| Density: | 1.91g/cm3 |
| Boiling Point: | 425.5°Cat760mmHg |
| Flash Point: | 162.2°C |
| Hazard Symbols: | Confirmed carcinogen and poison by ingestion. TLV: 0.05 mg/m3; animal carcinogen. |
| Risk Codes: | R25; R33; R40; R50/53; R39/23/24/25; R23/24/25; R11 |
| Safety: | Confirmed carcinogen with experimental carcinogenic data. Poison by ingestion and intravenous routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl−. See also HEPTACHLOR. |
| PSA: | 12.53000 |
| LogP: | 4.45270 |
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Chemistry
Empirical Formula: C10H5Cl7O
Molecular Weight: 389.3171
EINECS: 213-831-0
Index of Refraction: 1.661
Density: 1.91 g/cm3
Flash Point: 162.2 °C
Enthalpy of Vaporization: 65.39 kJ/mol
Boiling Point: 425.5 °C at 760 mmHg
Vapour Pressure: 4.71E-07 mmHg at 25 °C
Structure of Heptachlor epoxide (CAS NO.1024-57-3):
Product Categories of Heptachlor epoxide (CAS NO.1024-57-3): Baby Food Directives;Cyclodienes;Insecticides;Method Specific;Method Specific;Alpha sort;Oeko-Tex Standard 100;Pesticides & Metabolites
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cattle | LDLo | oral | 5mg/kg (5mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Economic Entomology. Vol. 52, Pg. 1127, 1959. |
| mouse | LD50 | intracrebral | 8mg/kg (8mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology Letters. Vol. 60, Pg. 289, 1992. |
| mouse | LD50 | oral | 39mg/kg (39mg/kg) | Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 27, 1966. | |
| mouse | LDLo | intravenous | 10mg/kg (10mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 107, Pg. 266, 1953. | |
| rabbit | LD50 | oral | 144mg/kg (144mg/kg) | "Pesticides Symposia; Collection of Papers Presented at the Sixth & Seventh Inter-American Conferences on Toxicology and Occupational Medicine, Miami, FL," Miami, FL, J.L. Halos, 1968-70Vol. 6, Pg. 231, 1968/1970. | |
| rat | LD50 | oral | 15mg/kg (15mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(2), Pg. 93, 1987. |
Consensus Reports
IARC Cancer Review: Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 20 , 1979,p. 129.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 5 , 1974,p. 173.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 20 , 1979,p. 129.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
Safety Profile
Confirmed carcinogen with experimental carcinogenic data. Poison by ingestion and intravenous routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl−. See also HEPTACHLOR.
Hazard Codes of Heptachlor epoxide (CAS NO.1024-57-3): 
T
N
F
Risk Statements: 25-33-40-50/53-39/23/24/25-23/24/25-11
R11:Highly flammable.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R25 :Toxic if swallowed.
R33:Danger of cumulative effects.
R39:Danger of very serious irreversible effects.
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 36/37-45-60-61-16-7
S7:Keep container tightly closed.
S16:Keep away from sources of ignition.
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
Standards and Recommendations
ACGIH TLV: TWA 0.05 mg/m3 (skin); Animal Carcinogen
Specification
Heptachlor epoxide ,its cas register number is 1024-57-3. It also can be called 4,7-Methanoindan, 1,4,5,6,7,8,8-heptachloro-2,3-epoxy-3a,4,7,7a-tetrahydro- ; 2,3,4,5,6,7,7-Heptachloro-1a,1b,5,5a,6,6a-hexahydro-2,5-methano-2H-indeno[1,2-b]oxirene ; and 1,6,8,9,10,11,11-Heptachlor-4-oxatetracyclo[6.2.1.0~2,7~.0~3,5~]undec-9-en .