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CAS No.: | 105047-45-8 |
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Name: | FMOC-LYS-OH |
Article Data: | 1 |
Molecular Structure: | |
Formula: | C21H24N2O4 |
Molecular Weight: | 368.433 |
Synonyms: | (2S)-6-Amino-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]hexanoicacid;N-a-(Fmoc)-N-e-(NH2)-L-Lysine-OH;Na-(9-Fluorenylmethoxycarbonyl)lysine;a-N-(9-Fluorenylmethyloxycarbonyl)lysine; |
Density: | 1.245 g/cm3 |
Melting Point: | 26.8 °C |
Boiling Point: | 607.6 °C at 760 mmHg |
Flash Point: | 321.3 °C |
Safety: | 24/25 |
PSA: | 101.65000 |
LogP: | 4.19850 |
The systematic name of Fmoc-L-lysine is (2S)-6-ammonio-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}hexanoate. With the CAS registry number 105047-45-8, it is also named as (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-aminohexanoic acid. The product's categories are Amino Acids; Lysine [Lys, K]; Fmoc-Amino Acids and Derivatives. In addition, its molecular formula is C21H24N2O4 and its molecular weight is 368.43. This chemical should be stored at 0 °C.
The other characteristics of Fmoc-L-lysine can be summarized as: (1)ACD/LogP: 3.19; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.68; (4)ACD/LogD (pH 7.4): 0.69; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 4.05; (8)ACD/KOC (pH 7.4): 4.07; (9)#H bond acceptors: 6; (10)#H bond donors: 4; (11)#Freely Rotating Bonds: 10; (12)Polar Surface Area: 66.84 Å2; (13)Index of Refraction: 1.6; (14)Molar Refractivity: 101.34 cm3; (15)Molar Volume: 295.9 cm3; (16)Polarizability: 40.17×10-24cm3; (17)Surface Tension: 56.2 dyne/cm; (18)Density: 1.245 g/cm3; (19)Flash Point: 321.3 °C; (20)Enthalpy of Vaporization: 94.94 kJ/mol; (21)Boiling Point: 607.6 °C at 760 mmHg; (22)Vapour Pressure: 1.29E-15 mmHg at 25 °C.
Uses of Fmoc-L-lysine: it can react with Benzaldehyde to get 6-Benzylamino-2-(9H-fluoren-9-ylmethoxycarbonyl)amino-1-hexanoic acid and 6-Dibenzylamino-2-(9H-fluoren-9-ylmethoxycarbonyl)amino-1-hexanoic acid.
This reaction needs NaBH(OAc)3 and 1,2-Dichloro-ethane at the temperature of 20 °C for 2 hours. The yield is 74 %.
People can use the following data to convert to the molecule structure.
(1)SMILES: [O-]C(=O)[C@@H](NC(=O)OCC3c1ccccc1c2c3cccc2)CCCC[NH3+]
(2)InChI: InChI=1/C21H24N2O4/c22-12-6-5-11-19(20(24)25)23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25)/t19-/m0/s1
(3)InChIKey: YRKFMPDOFHQWPI-IBGZPJMEBB
(4)Std. InChI: InChI=1S/C21H24N2O4/c22-12-6-5-11-19(20(24)25)23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25)/t19-/m0/s1
(5)Std. InChIKey: YRKFMPDOFHQWPI-IBGZPJMESA-N