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113-18-8

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Basic Information
CAS No.: 113-18-8
Name: ETHCHLORVYNOL CIV (0.7 ML)
Molecular Structure:
Molecular Structure of 113-18-8 (ETHCHLORVYNOL CIV (0.7 ML))
Formula: C7H9 Cl O
Molecular Weight: 144.601
Synonyms: 1-Chloro-3-ethyl-1-penten-4-yn-3-ol;3-(b-Chlorvinyl)-1-pentyn-3-ol;Alvinol; Arvynol; Ethchlorovynol; Ethchlorvinol; Ethchlorvynol; Ethclorvynol;Ethochlorvynol; Ethyl b-chlorovinyl ethynyl carbinol; NSC 30372; Normoson; Nostel; Placidyl;Roeridorm; Serenesil; Serensil
Density: 1.108g/cm3
Melting Point: 25°C
Boiling Point: 173.5°Cat760mmHg
Flash Point: 68.4°C
Hazard Symbols: Abuse may cause addiction.
Safety: Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: general anesthesia and thrombocytopenia (reduction in the number of blood platelets). Human effects on newborn by an unspecified route: drug dependency and Apgar score (condition of newborn). Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of Cl.
PSA: 20.23000
LogP: 1.51320
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Toxicity Data With Reference

1.   

orl-wmn TDLo:10 mg/kg:CNS

    BMJOAE    British Medical Journal. 2 (1962),1610.
2.   

orl-wmn TDLo:15 mg/kg/2D:BLD

    AIMEAS    Annals of Internal Medicine. 77 (1972),73.
3.   

scu-rat LD50:200 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,420.
4.   

orl-mus LD50:290 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 114 (1955),326.
5.   

ipr-mus LD50:275 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,420.
6.   

scu-mus LD50:240 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 114 (1955),326.
7.   

ivn-dog LD50:55 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,420.
8.   

orl-bwd LD50:42 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 21 (1972),315.

Safety Profile

Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: general anesthesia and thrombocytopenia (reduction in the number of blood platelets). Human effects on newborn by an unspecified route: drug dependency and Apgar score (condition of newborn). Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of Cl.