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CAS No.: | 115-26-4 |
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Name: | DIMEFOX |
Article Data: | 19 |
Molecular Structure: | |
Formula: | C4H12 F N2 O P |
Molecular Weight: | 154.124 |
Synonyms: | Phosphorodiamidicfluoride, tetramethyl- (6CI,7CI,8CI,9CI); BFPO;Bis(dimethylamido)fluorophosphate; Bis(dimethylamido)fluorophosphine oxide;Bis(dimethylamido)phosphoryl fluoride; Bis(dimethylamino)fluorophosphine oxide;Bis(dimethylamino)phosphorofluoridate; CR 409; DIFO; Dimefox; Fluorophosphoricacid di(dimethylamide); Hanane; N,N,N',N'-Tetramethylphosphorodiamidicfluoride; Pestox 14; Phosphine oxide, bis(dimethylamino)fluoro-; Terra-Sytam;Tetramethyldiamidophosphoric fluoride; Tetramethylphosphorodiamidic fluoride |
Density: | 1.111g/cm3 |
Boiling Point: | 156.9°Cat760mmHg |
Flash Point: | 48.7°C |
Hazard Symbols: | Cholinesterase inhibitor, use may be restricted. TLV: 2.5 mg(F)/m3. |
Risk Codes: | 27/28 |
Safety: | Poison by ingestion, skin contact, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of F−, NOx, and POx. |
Product Name: Dimefox (CAS NO.115-26-4)
Molecular Formula: C4H12FN2OP
Molecular Weight: 154.12g/mol
Mol File: 115-26-4.mol
Einecs: 204-076-8
Melting Point: 100 °C
Boiling point: 156.9 °C at 760 mmHg
Storage Temperature: +4°C
Flash Point: 2.83 mmHg at 25°C
Density: 1.111 g/cm3
Surface Tension: 29.9 dyne/cm
Enthalpy of Vaporization: 39.36 kJ/mol
Vapour Pressure: 2.83 mmHg at 25°C
XLogP3-AA: -0.1
H-Bond Donor: 0
H-Bond Acceptor: 4
IUPAC Name: N-[dimethylamino(fluoro)phosphoryl]-N-methylmethanamine
Canonical SMILES: CN(C)P(=O)(N(C)C)F
InChI: InChI=1S/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3
InChIKey: PGJBQBDNXAZHBP-UHFFFAOYSA-N
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LD50 | oral | 2mg/kg (2mg/kg) | BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | National Technical Information Service. Vol. PB158-508, |
dog | LD50 | intravenous | 5mg/kg (5mg/kg) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 112, Pg. 231, 1954. |
domestic animals - goat/sheep | LD50 | subcutaneous | 2mg/kg (2mg/kg) | BEHAVIORAL: COMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | National Technical Information Service. Vol. PB158-508, |
frog | LD50 | parenteral | 1410mg/kg (1410mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 124, Pg. 212, 1960. |
guinea pig | LD50 | intraperitoneal | 2500ug/kg (2.5mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 112, Pg. 231, 1954. | |
guinea pig | LD50 | oral | 4mg/kg (4mg/kg) | BEHAVIORAL: COMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | National Technical Information Service. Vol. PB158-508, |
guinea pig | LD50 | subcutaneous | 2mg/kg (2mg/kg) | BEHAVIORAL: COMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | National Technical Information Service. Vol. PB158-508, |
monkey | LD50 | oral | 2mg/kg (2mg/kg) | National Technical Information Service. Vol. PB158-508, | |
mouse | LD50 | intraperitoneal | 1350ug/kg (1.35mg/kg) | Journal of Agricultural and Food Chemistry. Vol. 13, Pg. 381, 1965. | |
mouse | LD50 | oral | 2mg/kg (2mg/kg) | Bulletin of the Entomological Society of America. Vol. 12, Pg. 161, 1966. | |
mouse | LD50 | subcutaneous | 1mg/kg (1mg/kg) | BEHAVIORAL: COMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | National Technical Information Service. Vol. PB158-508, |
rabbit | LD50 | intravenous | 3mg/kg (3mg/kg) | BEHAVIORAL: COMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | National Technical Information Service. Vol. PB158-508, |
rabbit | LD50 | oral | 3mg/kg (3mg/kg) | BEHAVIORAL: COMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | National Technical Information Service. Vol. PB158-508, |
rabbit | LD50 | subcutaneous | 6mg/kg (6mg/kg) | BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | National Technical Information Service. Vol. PB158-508, |
rat | LD50 | intraperitoneal | 5mg/kg (5mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 9, 1952. | |
rat | LD50 | oral | 1mg/kg (1mg/kg) | BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | National Technical Information Service. Vol. PB158-508, |
rat | LD50 | skin | 2mg/kg (2mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. | |
rat | LD50 | subcutaneous | 300ug/kg (0.3mg/kg) | National Technical Information Service. Vol. PB158-508, |
EPA Extremely Hazardous Substances List.
Safety Information of Dimefox (CAS NO.115-26-4):
Hazard Codes: T+
Risk Statements: 27/28
27: Very Toxic in contact with skin
28: Very Toxic if swallowed
Safety Statements: 23-28-36/37-38-45
23: Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)
28: After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36: Wear suitable protective clothing
37: Wear suitable gloves
38: In case of insufficient ventilation, wear suitable respiratory equipment
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
OSHA PEL: TWA 2.5 mg(F)/m3
ACGIH TLV: TWA 2.5 mg(F)/m3; BEI: 3 mg/g creatinine of fluorides in urine prior to shift; 10 mg/g creatinine of fluorides in urine at end of shift.
NIOSH REL: (Fluorides, Inorganic) TWA 2.5 mg(F)/m3
Dimefox ,its CAS NO. is 115-26-4,the synonyms is Bis(dimethylamido)-phosphoryl fluoride ; Bis(dimethylamino)fluorophosphate ; Bisdimethylaminofluorophosphine oxide ; CR 409 ; Caswell No. 843 ; DIFO ; EINECS 204-076-8 ; ENT 19,109 ; EPA Pesticide Chemical Code 443100 ; Fluophosphoric acid di(dimethylamide) ; Fluorure de N,N,N',N'-tetramethyle phosphoro-diamide .